DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut4 and ITR1

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_010785.1	Gene:	ITR1 / 852108	SGDID:	S000002905	Length:	584	Species:	Saccharomyces cerevisiae

Alignment Length:	475	Identity:	121/475 - (25%)
Similarity:	215/475 - (45%)	Gaps:	61/475 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FIV--GFIGALGAFCLG--------AVIGWSGPVENEVKNSNAYNFTPRQTEWGLVGSLMTLGAA 61
            ||:  .|:.::..|..|        |:|.....::::|       .|..:.|  :|.:..:|||.
Yeast    85 FIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKV-------LTYGEKE--IVTAATSLGAL 140

  Fly    62 FSCIPVGVLIGKIGRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVT 126
            .:.|..|......|||..::.....|.||.:|.:.|.....:.:||.::||..|...:..|::::
Yeast   141 ITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGSLIAPLFIS 205

  Fly   127 EIAQVQYRGTMGCFFQLLIVFGILYAFVVGGFVKTFYFN------IACAILP-VIFFVLMIFMPE 184
            |||....||.:.....|.:..|.|.|:..|..:.  |.|      :..:::| .:.|..:.|:|:
Yeast   206 EIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLN--YVNNGWRILVGLSLIPTAVQFTCLCFLPD 268

  Fly   185 SPIFLAQKGKAEKAEKSLKFLRGKDADVSGELKEMSAEG--QKEKASVGKILCRRI--------- 238
            :|.:...||...:|.:.||   ....|.|.|:.|...|.  ...::..||.:..::
Yeast   269 TPRYYVMKGDLARATEVLK---RSYTDTSEEIIERKVEELVTLNQSIPGKNVPEKVWNTIKELHT 330

  Fly   239 ---TLKGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVI 300
               .|:.|.:..||...||.||.|:::::|..||||.|......:|.|:.| ...|.|:::...|
Yeast   331 VPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSG-TNFIFTLVAFFSI 394

  Fly   301 EKVGRKILLLVSACMMGISTLIMALYF-----------GMLMKSGV---GWLALIAVCVFIIGFS 351
            :|:||:.:||:....|.::.::.::.|           .:::.||.   |.:.::.:.||...::
Yeast   395 DKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKFDGAVAVVVSSGFSSWGIVIIVFIIVFAAFYA 459

  Fly   352 LGFGPVPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAA 416
            ||.|.||| ..:|||.::|:.:..|.|..|||..:.::...|..:...|.....||.|.|.:..:
Yeast   460 LGIGTVPW-QQSELFPQNVRGIGTSYATATNWAGSLVIASTFLTMLQNITPAGTFAFFAGLSCLS 523

  Fly   417 FVFILFLIPETKGKTLNEIQ 436
            .:|..|..||..|..|.|:|
Yeast   524 TIFCYFCYPELSGLELEEVQ 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	118/471 (25%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	106/411 (26%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	112/456 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13428
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740