DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and CIN10

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_010675.3	Gene:	CIN10 / 851995	SGDID:	S000002795	Length:	555	Species:	Saccharomyces cerevisiae

Alignment Length:	501	Identity:	115/501 - (22%)
Similarity:	207/501 - (41%)	Gaps:	82/501 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FIGA-LGAFCLGAVIGWSGPVENEVKNSNAYNFTPRQTEWGLVGSLMTLGAAFSCIPVGVLIGKI 74
            |:|| :|....|...|....|...:|..:.........:..|:.|..::|:.|..|....|..:.
Yeast    43 FVGATIGGLLFGYDTGVISGVLLSLKPEDLSLVVLTDVQKELITSSTSVGSFFGSILAFPLADRY 107

  Fly    75 GRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVTEIAQVQYRGTMGC 139
            ||:.|:.|....|.:..:.:.:|..:..|:.||.:||...|......|::::||:..:.||.|..
Yeast   108 GRRITLAICCSIFILAAIGMAIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRGFMLT 172

  Fly   140 FFQLLIVFGILYAFVVGGFVK----TFYFNIACAILPVIFFV-LMIFMPESPIFLAQKGKAEKAE 199
            ...:.|..|.|.::|:...:|    ::.:..|.:.:|.|.|: ::.|:||||.:...||......
Yeast   173 LNIIAITGGQLVSYVIASLMKEIDNSWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTR 237

  Fly   200 KSLKFL-----------------------------------------RGKDADVSGEL-----KE 218
            .||:.|                                         |..|:..||.|     |.
Yeast   238 DSLRMLYPTASTYHVNSKIKQLIIELDKLRLYEDASEPLLVQSQSVIRYMDSSTSGTLSPPNIKR 302

  Fly   219 MSAEGQKEK----------------ASVGKILCRR--------ITLKGLFLSIGLMLFQQMTGIN 259
            :|:..::..                |..|.:...:        .|::.|.:...||.|||:||.|
Yeast   303 LSSNTERTSNTMSSSSAYLSALRGPAPNGALASNKKKRHRMEPRTIRALIVGCMLMFFQQITGFN 367

  Fly   260 AIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVIEKVGRKILLLVSACMMGISTLIMA 324
            |.::|:..|| :..:...|.:..|::.....|.|..::..::.:||:.:||.:..:|.:..|:.:
Yeast   368 AFMYYAAIIF-SKFNIKNPLLPPILIASTNFIFTFFAMYTMDSLGRRAILLRTILIMTVGLLLCS 431

  Fly   325 LYFGMLMKSGVGWLALIAVCVFIIGFSLGFGPVPWLMMAELFAEDVKALAGSIAGTTNWCFAFIV 389
            :.||....:    |.||:|.:::..::...|.|||..: |....:.::...|....|||.....|
Yeast   432 VGFGHDQVN----LLLISVVIYVAAYASAMGSVPWTCV-EFLPLNRRSFGASCIACTNWLTNAFV 491

  Fly   390 TLLFPVLNDIIGATACFAIFFGFAVAAFVFILFLIPETKGKTLNEI 435
            ::.:....:.||......||..|.|.|:.|:.|..||.||.:|.|:
Yeast   492 SMTYLSTINTIGDENTMLIFAFFTVCAWFFVYFWYPEVKGLSLEEV 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	115/501 (23%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	101/451 (22%)
CIN10	NP_010675.3	MFS_HMIT_like	45..528	CDD:340918	108/488 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342255
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13428
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740