DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and SNF3

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	461	Identity:	143/461 - (31%)
Similarity:	213/461 - (46%)	Gaps:	42/461 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VGFIGALGAFCLGAVIGWSGPVE--NEVKNSNAYN---FTPRQTEWGLVGSLMTLGAAFSCIPVG 68
            ||...|:|.|..|...|....:.  |.||:..|.|   ||.:|  ..::.|.::||..|..:...
Yeast   100 VGVFVAVGGFLFGYDTGLINSITSMNYVKSHVAPNHDSFTAQQ--MSILVSFLSLGTFFGALTAP 162

  Fly    69 VLIGKIGRKTTML---ILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVTEIAQ 130
            .:....|||.|::   |.:  |.||..|.:.|..|.:|::||.:.|...||.....|:|..|...
Yeast   163 FISDSYGRKPTIIFSTIFI--FSIGNSLQVGAGGITLLIVGRVISGIGIGAISAVVPLYQAEATH 225

  Fly   131 VQYRGTMGCFFQLLIVFGILYAFVVG------GFVKTFYFNIACAILPVIFFVL-MIFMPESPIF 188
            ...||.:...:|..|.:|:|.:..|.      ....::...|....:...|..: |.|:||||.:
Yeast   226 KSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYRIPIGLQYVWSSFLAIGMFFLPESPRY 290

  Fly   189 LAQKGKAEKAEKSLKFLRGKDADVSG---ELKEMSAEGQKEKASVGK---ILC-------RRITL 240
            ...|.|.::|.|||.||||.....||   ||.|:.|....| ||.|.   |.|       .:.||
Yeast   291 YVLKDKLDEAAKSLSFLRGVPVHDSGLLEELVEIKATYDYE-ASFGSSNFIDCFISSKSRPKQTL 354

  Fly   241 KGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVIEKVGR 305
            : :|..|.|..|||.:|||.|.:|....|...|.:....:| .|...|..:..:..:..:|..||
Yeast   355 R-MFTGIALQAFQQFSGINFIFYYGVNFFNKTGVSNSYLVS-FITYAVNVVFNVPGLFFVEFFGR 417

  Fly   306 KILLLVSACMMGISTLIMALYFGMLMKSGVGWLALIA-VCVFIIGFSLGFGPVPWLMMAELFAED 369
            :.:|:|...:|.|:..|:|: .|..:|:......:|| :|:||..||..:|.|.|::.|||:...
Yeast   418 RKVLVVGGVIMTIANFIVAI-VGCSLKTVAAAKVMIAFICLFIAAFSATWGGVVWVISAELYPLG 481

  Fly   370 VKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFA--IFF--GFAVAAFVFILFL-IPETKG 429
            |::...:|....||...||..|:.|.:.|....|:...  |||  |...|..|.:::| :.||||
Yeast   482 VRSKCTAICAAANWLVNFICALITPYIVDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVYETKG 546

  Fly   430 KTLNEI 435
            .||.||
Yeast   547 LTLEEI 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	143/461 (31%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	120/405 (30%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	143/461 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342263
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	7	6.640