DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut4 and slc2a6

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	XP_689092.6	Gene:	slc2a6 / 560602	ZFINID:	ZDB-GENE-081104-301	Length:	490	Species:	Danio rerio

Alignment Length:	472	Identity:	141/472 - (29%)
Similarity:	227/472 - (48%)	Gaps:	62/472 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FIVGFIGALGAFCLGAVIGWSGPVENEVK--NSNAYNFTPRQTEWGLVGSLMTLGAAFSCIPVGV 69
            ::..|...||.|..|..:.:..||..::|  :.........|..|  .||:.|||||...:....
Zfish    25 YLAVFSAVLGNFNFGFALVFPSPVIPQLKQGDDTRLQMNVHQISW--FGSIFTLGAAAGGLSAMF 87

  Fly    70 LIGKIGRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVTEIAQVQYR 134
            |..::|||.:::|...|..:|.|::..|.:..|||.|||:.|..||....:.|:||:||:....|
Zfish    88 LNDRVGRKISIMISGLPSVLGLLVMGSAQNFWMLLWGRFLTGIAGGITAGSIPVYVSEISHPSVR 152

  Fly   135 GTMGCFFQLLIVFGILYAFVVGGFVKTFYFNIACAILPVIFFVLMIFMPESPIFLAQKGKAEKAE 199
            |.:|...|:..|||.|..:..|..:...:..:|..:..||..:|:..||.||.:...||...||.
Zfish   153 GALGSCPQITAVFGSLALYAFGLILPWRWLAVAGEVPVVIMMLLLCCMPTSPRYHIMKGNRAKAV 217

  Fly   200 KSLKFLRGKDADVSGELKEMSAEGQKEKASVGKILCRRITLKG--------------LFLSIGLM 250
            |||::|||.::|...|..::.               |.||.:|              :.:|:.:.
Zfish   218 KSLEWLRGPNSDYMTEFNKIE---------------RSITTQGVQWSDLKTKSYYKPILISVVMR 267

  Fly   251 LFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVIEKVGRKILLLVSACM 315
            ..||||||..|:.|...||.....:|||:....:||.|:.|:..|:..:::|.|||.||..|..:
Zfish   268 FLQQMTGITPILVYLEPIFHLTAISLEPKYDAALVGAVRLISVAIAASLMDKAGRKALLFTSGFL 332

  Fly   316 MGISTLIMALYF-------GML-----------MKSGVGW-----LALIAVCVFIIGFSLGFGPV 357
            :.|:.|.|.:|.       |.|           :::|..:     :.||:..|.|.|:::|:||:
Zfish   333 IYIAMLSMTMYTHQTPCSQGNLTLTDGLNISSEVQAGAAFDPKTLIPLISAMVIIFGYAMGWGPI 397

  Fly   358 PWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFILF 422
            .||:|:|:.....:.:|..:....:|..||::|.||   ..::.|...:..|..|.|.:.|.|:|
Zfish   398 TWLLMSEILPLGARGVASGLCVGVSWITAFVLTQLF---MHVVVAYGLYVPFLFFCVVSVVNIIF 459

  Fly   423 ---LIPETKGKTLNEIQ 436
               .:|||||:||.||:
Zfish   460 TAKCVPETKGRTLEEIE 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	140/468 (30%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	123/416 (30%)
slc2a6	XP_689092.6	Sugar_tr	27..479	CDD:278511	141/470 (30%)
slc2a6	XP_689092.6	MFS	28..461	CDD:119392	132/452 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576883
Domainoid	1	1.000	292	1.000	Domainoid score	I1492
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2576
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	1	1.000	-	-		mtm6527
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.800