DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and slc2a1a

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001034897.1	Gene:	slc2a1a / 555778	ZFINID:	ZDB-GENE-030131-3158	Length:	488	Species:	Danio rerio

Alignment Length:	473	Identity:	155/473 - (32%)
Similarity:	246/473 - (52%)	Gaps:	57/473 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ALGAFCLGAV-IGWSGPVENEVKN----------SNAYNF----TPRQTEWGLVGSLMTLGAAFS 63
            |:|...:|:: .|::..|.|..:.          .|.|:.    |...|.|.:..::.::|....
Zfish    15 AVGTAVIGSLQFGYNTGVINAPQKIIEGFYNETWHNRYSEYIPPTTLTTLWSVSVAIFSVGGILG 79

  Fly    64 CIPVGVLIGKIGRKTTMLI-----LLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPM 123
            ...||:.:.:.||:.:|||     .:...|:|:  ..||....||::|||:||...|......||
Zfish    80 SFSVGLFVNRFGRRNSMLIANILAFIAAAFMGF--SKLAESWEMLIIGRFIVGLYSGLSTGFVPM 142

  Fly   124 YVTEIAQVQYRGTMGCFFQLLIVFGILYAFVVG-----------GFVKTFYF---NIACAILPVI 174
            ||.|||....||.:|...||.||.|||.|.:.|           .|:..|.|   .:.||:||
Zfish   143 YVGEIAPTSLRGALGTLHQLGIVIGILMAQIFGIKEIMGSPTLWPFMLGFTFIPAVLQCALLP-- 205

  Fly   175 FFVLMIFMPESPIF-LAQKGKAEKAEKSLKFLRGKDADVSGELKEMSAEGQ---KEK-ASVGKIL 234
                  |.||||.: |..:.:..||:..||.|||.| ||..:::||..|.:   :|| .::.::.
Zfish   206 ------FCPESPRYLLINQNEEAKAKSVLKKLRGTD-DVGADMQEMRDESRQMMREKTVTIPELF 263

  Fly   235 CRRITLKGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILV 299
            ...:..:.:|::|.|.|.||.:||||:.:|||.|||.||.: ||..:||..|.|....|::|:.:
Zfish   264 RSSLYRQPIFIAIMLQLSQQFSGINAVFYYSTGIFEKAGVS-EPVYATIGAGAVNTAFTVVSLFI 327

  Fly   300 IEKVGRKILLLVSACMMGISTLIMALYFGMLMKSGVGWL---ALIAVCVFIIGFSLGFGPVPWLM 361
            :|:|||:.|.||....|.:|:::|.:...:|.|  |.|:   :::|:..|:..|.:|.||:||.:
Zfish   328 VERVGRRSLHLVGLMGMAVSSVLMTIAMALLTK--VEWMSYVSIVAIFSFVAFFEIGPGPIPWFI 390

  Fly   362 MAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFILFLIPE 426
            :||||::..:..|.::||.:||...|:|.:.|..:.::.|... |.||....:..|||..|.:||
Zfish   391 VAELFSQGPRPSAFAVAGFSNWFANFLVGMCFQYVEELTGPYV-FIIFTVLLLIFFVFTYFKVPE 454

  Fly   427 TKGKTLNEIQAKMGEKAE 444
            |||::..||.|.....|:
Zfish   455 TKGRSFEEITASFRTGAD 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	152/463 (33%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	137/403 (34%)
slc2a1a	NP_001034897.1	Sugar_tr	18..467	CDD:278511	152/463 (33%)
slc2a1a	NP_001034897.1	MFS	62..450	CDD:119392	136/402 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740