DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and slc2a5

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_001008187.1	Gene:	slc2a5 / 493549	XenbaseID:	XB-GENE-494009	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	474	Identity:	151/474 - (31%)
Similarity:	245/474 - (51%)	Gaps:	43/474 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TATQFIVGFIGALG-AFCLG---AVIGWSGPVENEVKNSNAYNFTPRQTE-------WGLVGSLM 56
            |||..:|..:...| :|..|   |.:....|...:..||..........|       |.|..||.
Frog    18 TATLILVTLVATFGSSFQYGYNVASVNSPSPFMKDFYNSTNIERVGSPLEDAFLTLLWSLTVSLY 82

  Fly    57 TLGAAFSCIPVGVLIGKIGRKTTMLI-----LLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGA 116
            .||..|..:.||.|:.|:|||.|:|.     ::|...:|..::  |....:::..|..||.|.|.
Frog    83 PLGGFFGSLLVGPLVSKLGRKGTLLFNNIFSIIPAILMGTSVV--AKTFEVIIASRLFVGVCAGL 145

  Fly   117 FCVTCPMYVTEIAQVQYRGTMGCFFQLLIVFGILYAFVVG-----GFVKTFYFNIACAILP-VIF 175
            .....||||.|::....||.:|...||:|..|||.|.:.|     |..:.:...:|...:| |:.
Frog   146 SSNVVPMYVGEMSPKNLRGAIGIMPQLMITVGILMAQIFGIRYILGNTEGWPILLALTGIPAVLE 210

  Fly   176 FVLMIFMPESPIF-LAQKGKAEKAEKSLKFLRGKDADVSGELKEMSAEGQKEKASVGKI----LC 235
            ...:.|.||||.: |..||..:||:|:|:.|||.: ||..|:|||..|.|.|||. |::    ||
Frog   211 LAFLPFFPESPRYTLLHKGNEDKAKKALQRLRGWE-DVDSEIKEMYQEDQSEKAE-GQLSVRNLC 273

  Fly   236 RRITLKGLFLSIGLM-LFQQMTGINAIIFYSTFIFETAGSTLEP-RISTIIVGIVQAIATIISIL 298
            ....|:...:||.:| :.||::||||:.:|:..|:::||...|. :..|:..|.|..:.|:.::.
Frog   274 TFRPLRWQLISIIVMNMGQQLSGINAVYYYADSIYKSAGVKEETIQYVTVATGSVNVLMTLAAVF 338

  Fly   299 VIEKVGRKILLL--VSACMMGISTLIMALYFGMLMKSGVGW---LALIAVCVFIIGFSLGFGPVP 358
            :::..||::|||  ...|.:....|.:||.:    ::.|.|   |::..:.:::||.::|..|:|
Frog   339 IVDSWGRRVLLLSGFGTCCISCVVLTIALVY----QTTVSWMPYLSIACIIIYVIGHAIGPSPIP 399

  Fly   359 WLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFILFL 423
            :::..|:|.:..:..|..|||:.:|...||:.|:|..|.:.:|| .||.:|....:|.|:||..:
Frog   400 YVITTEMFRQASRPAAFMIAGSVHWLSNFIIGLIFEFLMNGLGA-YCFILFAAICLATFIFIYIV 463

  Fly   424 IPETKGKTLNEIQAKMGEK 442
            :|||||||..|:...|.::
Frog   464 VPETKGKTFLEVSQLMAKR 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	147/460 (32%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	131/406 (32%)
slc2a5	NP_001008187.1	MFS_GLUT_Class2	24..475	CDD:340990	146/459 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910