DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and Glut1

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_612073.2	Gene:	Glut1 / 38109	FlyBaseID:	FBgn0264574	Length:	1440	Species:	Drosophila melanogaster

Alignment Length:	461	Identity:	134/461 - (29%)
Similarity:	226/461 - (49%)	Gaps:	44/461 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FIGALGAFCLGAVIGWSGPVENEVKNSNAYNFTPRQTE----------WGLVGSLMTLGAAFSCI 65
            |...||....|...|.....|..::|.....:..|..|          :.:..|:..:|......
  Fly    18 FSAVLGMLQFGYNTGVINAPEKNIENFMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGGMLGGF 82

  Fly    66 PVGVLIGKIGRKTTMLI-----LLPPFFIGWLLILLASH-IAMLLLGRFVVGFCGGAFCVTCPMY 124
            ..|.:..:.|||..:|:     :.....:|:..:   || ..||.||||::|...|......|||
  Fly    83 SGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKV---SHSYEMLFLGRFIIGVNCGLNTSLVPMY 144

  Fly   125 VTEIAQVQYRGTMGCFFQLLIVFGILYAFVVG-----GFVKTFYFNIACAILPVIF-FVLMIFMP 183
            ::|||.:..||.:|...||.:..|:|.:.|:|     |..:.:...:..||.|.|. .:|:...|
  Fly   145 ISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQLILLPVCP 209

  Fly   184 ESPIF-LAQKGKAEKAEKSLKFLRGKDADVSGELKEMSAEGQKEKA----SVGKILCRRITLKGL 243
            |||.: |..|...|:|.|:|:.||. ...|..:::||.||.:.:::    |..:::|.......|
  Fly   210 ESPRYLLITKQWEEEARKALRRLRA-SGSVEEDIEEMRAEERAQQSESHISTMELICSPTLRPPL 273

  Fly   244 FLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLE-PRISTIIVGIVQAIATIISILVIEKVGRKI 307
            .:.|.:.|.||.:||||:.:|||.:|.::|.|.| .:.:||.:|.:..:.|::||.::::.||:.
  Fly   274 IIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMDRTGRRT 338

  Fly   308 LLLVSACMMGISTLIMALYFGMLMKSGVGW---LALIAVCVFIIGFSLGFGPVPWLMMAELFAED 369
            |.|.....|.|.::.:.:.|  |:|..:.|   |:::|...|::.|::|.|.:||::.||||::.
  Fly   339 LHLYGLGGMFIFSIFITISF--LIKEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQG 401

  Fly   370 VKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFILFL---IPETKGKT 431
            .:..|.:||...||...|:|.:.||.:...:....    |..|:|...:|.:|.   :||||.||
  Fly   402 PRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYT----FLPFSVFLAIFWIFTYKKVPETKNKT 462

  Fly   432 LNEIQA 437
            ..||.|
  Fly   463 FEEILA 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	132/458 (29%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	117/410 (29%)
Glut1	NP_612073.2	MFS	17..452	CDD:119392	125/443 (28%)
Glut1	NP_612073.2	Sugar_tr	18..470	CDD:278511	134/461 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13833
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	4	3.810