DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	XP_006237357.1	Gene:	Slc2a3 / 25551	RGDID:	3706	Length:	495	Species:	Rattus norvegicus

Alignment Length:	467	Identity:	146/467 - (31%)
Similarity:	239/467 - (51%)	Gaps:	46/467 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IGALGAFCLGAVIGWSGPVENEVKNSNAYNFTPR----------QTEWGLVGSLMTLGAAFSCIP 66
            :..:|:|..|...|.....|..:|:...|....|          .|.|.|..::.::|.......
  Rat    18 VATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGLLTTLWSLCVAIFSVGGMIGSFS 82

  Fly    67 VGVLIGKIGRKTTMLILLPPFFIGWLLI---LLASHIAMLLLGRFVVGFCGGAFCVTC----PMY 124
            ||:.:.:.||:.:||::.....:|..|:   .:|..:.||:|||.::|.    ||..|    |||
  Rat    83 VGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGI----FCGLCTGFVPMY 143

  Fly   125 VTEIAQVQYRGTMGCFFQLLIVFGILYAFVVG-----GFVKTFYFNIACAILPVIF-FVLMIFMP 183
            :.|::....||..|...||.||.|||.|.|.|     |..:.:...:...|:|.|. ...:.|.|
  Rat   144 IGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCP 208

  Fly   184 ESPIFLAQKGKAE-KAEKSLKFLRGKDADVSGELKEMSAE----GQKEKASVGKILCRRITLKGL 243
            |||.||....|.| :|.:.|:.|.| ..||..|::||..|    .|:::.:|.::.......:.|
  Rat   209 ESPRFLLINRKEEDQATEILQRLWG-TPDVIQEIQEMKDESIRMSQEKQVTVLELFKSPSYFQPL 272

  Fly   244 FLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVIEKVGRKIL 308
            .:|:.|.|.||.:||||:.:|||.||:.|| ..||..:||..|:|..|.|::|:.::|:.||:.|
  Rat   273 LISVVLQLSQQFSGINAVFYYSTGIFQDAG-VQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTL 336

  Fly   309 LLVSACMMGISTLIMALYFGMLMK---SGVGWLALIAVCVFIIGFSLGFGPVPWLMMAELFAEDV 370
            .::....|.:.::.|.:  .:|:|   ..:.::.::|:.|::..|.:|.||:||.::||||::..
  Rat   337 HMIGLGGMAVCSVFMTI--SLLLKDEYEAMSFVCIVAILVYVAFFEIGPGPIPWFIVAELFSQGP 399

  Fly   371 KALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFILFLIPETKGKTLNEI 435
            :..|.::||.:||...|:|.:.||.....:||.. |.||..|.|...:|..|.:|||||:|..:|
  Rat   400 RPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYV-FIIFAAFLVFFLIFTFFKVPETKGRTFEDI 463

  Fly   436 ------QAKMGE 441
                  ||:.|:
  Rat   464 TRAFEGQAQSGK 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	143/460 (31%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	128/397 (32%)
Slc2a3	XP_006237357.1	Sugar_tr	15..467	CDD:278511	143/457 (31%)
Slc2a3	XP_006237357.1	MFS	16..450	CDD:119392	135/440 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337680
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740