DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut4 and itr1

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_593858.2	Gene:	itr1 / 2543145	PomBaseID:	SPAC4F8.15	Length:	575	Species:	Schizosaccharomyces pombe

Alignment Length:	469	Identity:	119/469 - (25%)
Similarity:	214/469 - (45%)	Gaps:	56/469 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FIVGFIGALGAFCLG----------AVIGWS--GPVENEVKNSNAYNFTPRQTEWGLVGSLMTLG 59
            :::.|...:|....|          .|||.|  |   :|:.|......|          |..:||
pombe    88 WVLAFAAGIGGLLFGYDTGVISGALVVIGTSLGG---HELTNGGKEFIT----------SATSLG 139

  Fly    60 AAFSCIPVGVLIGKIGRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMY 124
            |....|..|.|....|||..:.|......:|.::.:.|.|:..:::||||:|:..|...:..|:|
pombe   140 ALLGGIIAGALADFFGRKPVIAIASIIIIVGSIVQVTAHHLWHMIVGRFVIGWGVGIASLIIPLY 204

  Fly   125 VTEIAQVQYRGTMGCFFQLLIVFGILYAFVVGGFVKTFY----FNIACAILPVIF-FVLMIFMPE 184
            ::|||..:.||.:...:.|||..|.:.|:.:....:..:    :.:..|::|..| ..::|::||
pombe   205 LSEIAPSKIRGRLVIIYVLLITAGQVIAYGIDTAFEHVHNGWRWMVGLAMVPAAFQLFILIWLPE 269

  Fly   185 SPIFLAQKGKAEKAEKSLK--FLRGKDADVSGELKEMSAEG----------QKEKASVGKILCRR 237
            ||..|.:|.::::|..:|.  :......::..:| .:..||          ||...:..::....
pombe   270 SPRLLVKKERSQEAYNTLARIYPTAHPYEIKTKL-YLIQEGVRDPFSGSRWQKIVKTFKELYFNP 333

  Fly   238 ITLKGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVIEK 302
            ...:.|.|:.||...||::|.|:::::|:.|||..|.. .|..:.:|:.....:.||::..||:.
pombe   334 SNFRALILACGLQAMQQLSGFNSLMYFSSTIFEVVGFN-NPTATGLIIAATNFVFTIVAFGVIDF 397

  Fly   303 VGRKILLLVSACMMGISTLIMALYFGMLMKSGVG---------W--LALIAVCVFIIGFSLGFGP 356
            .||:||||::...|..:.::.|:.|..|.|...|         |  :.||::.|::..::.|.|.
pombe   398 FGRRILLLLTVWGMIAALIVCAVAFHFLPKDENGNYTSGQSNAWAIVVLISMIVYVASYASGLGN 462

  Fly   357 VPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFIL 421
            :|| ..:|||...|:.|...::...||.....:...|..|...|..|..||::.|.....::..|
pombe   463 LPW-QQSELFPMSVRGLGTGMSTAVNWAGNLGIGASFLTLMSEITPTGTFALYGGLCFLGWLGAL 526

  Fly   422 FLIPETKGKTLNEI 435
            |..|:....|:.||
pombe   527 FCYPDLTDYTIEEI 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	119/467 (25%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	104/404 (26%)
itr1	NP_593858.2	Sugar_tr	90..544	CDD:278511	119/467 (25%)
itr1	NP_593858.2	MFS	92..529	CDD:119392	115/452 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	179	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	184	1.000	Inparanoid score	I1095
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13833
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860