DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut4 and ght4

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_595064.1	Gene:	ght4 / 2539710	PomBaseID:	SPBC1683.08	Length:	557	Species:	Schizosaccharomyces pombe

Alignment Length:	485	Identity:	121/485 - (24%)
Similarity:	213/485 - (43%)	Gaps:	72/485 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MG-TATQFIVGFI---GALGAFCLGAVIGWSGPVE---------NEVKNSNAYNFTPRQTEW--G 50
            || |.|..:|.||   |.||....|::.|..|..:         |.:.||.:|      :.|  .
pombe     1 MGRTLTSVLVVFISMAGWLGGADTGSISGILGMRDFQSRFADRYNPITNSYSY------SAWRQA 59

  Fly    51 LVGSLMTLGAAFSCIPVGVLIGKIGRKTTMLILLPPFFIGWLLILLA-SHIAMLLLGRFVVGFCG 114
            |:...:..|..|..:........||:|.::......:.||.:|::.| .....:::|:...|...
pombe    60 LLTGTVNAGCLFGAMLSSPFTEAIGKKYSIAFFSGCYIIGQILLVTAVPSWVQIMVGKLFTGLTI 124

  Fly   115 GAFCVTCPMYVTEIAQVQYRGTMGCFFQLLIVFGILYAFVV----------GGFVKTFYFNIACA 169
            ||..|..|.|.:|:|..|.||.:...:||....|.|.|..:          ..:..:|..||
pombe   125 GALSVLSPGYQSEVAPPQIRGAVVSTYQLFQTCGTLIAACINMGTHKLRKTASWRTSFGINI--- 186

  Fly   170 ILPVIFFVLMIFMPESPIFLAQKGKAEKAEKSLKFLRGKDADVSGEL-----------KEMSAEG 223
            :..:...|.::|:||||.:|..||:.|:|.:.:  .:..:.|...|:           .||...|
pombe   187 LWGIFLMVGVLFLPESPRYLIYKGRDEEALRIM--CQTAELDPESEIIQTNFNTIKSDIEMEMAG 249

  Fly   224 QKEK--ASVGKILCRRITLKGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVG 286
            .|.:  ...||.:..|..|.  ||:   ||.:::.|.|...:|:|.:|:..|.| :..:..:|:|
pombe   250 GKARWPEVFGKEVRYRTVLG--FLT---MLLRELIGNNYYFYYATQVFKGTGMT-DIFLPAVILG 308

  Fly   287 IVQAIATIISILVIEKVGRKILLLVSACMMGISTLIMALYFG--MLMKSG-----VGWLALIAVC 344
            .:....|..::..|:.:||:..|:..|....|...|.|....  ::.|:|     .|.:.::..|
pombe   309 AINFGTTFGALYTIDNLGRRNPLIFGAAFQSICFFIYAAVGDRKLIYKNGTSDHRAGAVMIVFSC 373

  Fly   345 VFIIGFSLGFGPVPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIF 409
            :|:..:...:||:.|:::.|.|....::...::|.:.||...|:|:...|.:::.||    |.:.
pombe   374 LFLFSYCCSWGPMGWVIVGETFPIRYRSKCAAVATSGNWLGNFMVSFFTPFISNSIG----FKLG 434

  Fly   410 FGFA----VAAFVFILFLIPETKGKTLNEI 435
            :.:|    .:||. |..:..||||.||.|:
pombe   435 YIYACINMTSAFQ-IFLMAKETKGLTLEEV 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	117/476 (25%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	97/413 (23%)
ght4	NP_595064.1	Sugar_tr	9..467	CDD:278511	117/477 (25%)
ght4	NP_595064.1	MFS	10..440	CDD:119392	107/450 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.710