DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut4 and ght6

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_587739.1	Gene:	ght6 / 2538845	PomBaseID:	SPCC1235.13	Length:	535	Species:	Schizosaccharomyces pombe

Alignment Length:	477	Identity:	127/477 - (26%)
Similarity:	204/477 - (42%)	Gaps:	80/477 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ALGAFCLGAVIGWSGPVEN-------------EVKNSNAYNFTPRQTEWGLVGSLMTLGAAFSCI 65
            ::..:..||..|..|.:.|             .|.::.:|: :.||   ||:..::..|....|:
pombe    14 SMAGWMFGADTGSIGGITNMRDFQSRYADRYDPVTDTYSYS-SARQ---GLLVGMVNTGTTVGCL 74

  Fly    66 ---PVGVLIGKIGRKTTMLILLPPFFIGWLLILLASHIAML---------LLGRFVVGFCGGAFC 118
               |:|...||  ||..|         ||.|:.:...|..|         ::.:...|...||..
pombe    75 LSSPLGDRFGK--RKCIM---------GWTLVYITGVIVQLTTIPSWVQMMVAKIWTGLGIGALS 128

  Fly   119 VTCPMYVTEIAQVQYRGTMGCFFQLLIVFGILYAFVV--GGFVKTFY----------FNIACAIL 171
            |..|.|.:|.:....||.:...:||.|..||..|..:  |....|.:          .|:...||
pombe   129 VIAPGYQSESSPPHIRGAIVTTYQLFITLGIFIAACINMGTHKYTTHPEAQWRVPIGINLLWGIL 193

  Fly   172 PVIFFVLMIFMPESPIFLAQKGKAEKAEKSLKFLRGKDAD---VSGELKEMSAEGQKEKA----S 229
               .|..|:|:||||.:||.||:.|:..|.|....|..||   :..|...:.|:.:.|.|    |
pombe   194 ---MFFGMLFLPESPRYLAVKGRNEECMKILTRNAGLPADHPIMQKEYNAIQADVEAELAGGPCS 255

  Fly   230 VGKILCRRITLKGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATI 294
            ..:|....|..:.| |.:|:|.|||:||.|...:|.|.:|...|.. .|.::.:|:..|....|.
pombe   256 WPQIFSNEIRYRTL-LGMGVMAFQQLTGNNYFFYYGTQVFRGTGLN-SPFLAALILDAVNFGCTF 318

  Fly   295 ISILVIEKVGRKILLLVSACMMGISTLIMALY--FGMLMKSG-----VGWLALIAVCVFIIGFSL 352
            .:|.|:|..||:..|:|......|...|.|..  ..:...:|     .|.:.::..|:||..|:.
pombe   319 GAIFVLEYFGRRGPLIVGGVWQSICFFIYASVGDRALTRPNGTSNHRAGAVMIVFSCLFIFSFAQ 383

  Fly   353 GFGPVPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAV--- 414
            .:.|..::::.|.:....::...::|..:||.:.|:::...|.:::.||    |...:.||.
pombe   384 TWAPAAYVIVGESYPIRYRSKCAAVATASNWFWNFMISFFTPFISNSIG----FKYGYVFAACNL 444

  Fly   415 -AAFVFILFLIPETKGKTLNEI 435
             ||.:..|| ..||||.||.||
pombe   445 CAAIIIFLF-AKETKGLTLEEI 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	127/477 (27%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	110/418 (26%)
ght6	NP_587739.1	MFS	10..453	CDD:119392	117/462 (25%)
ght6	NP_587739.1	Sugar_tr	11..469	CDD:278511	127/477 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9279
orthoMCL	1	0.900	-	-		OOG6_100060
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.800