DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment sut4 and C35A11.4

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_504430.2	Gene:	C35A11.4 / 178921	WormBaseID:	WBGene00016431	Length:	515	Species:	Caenorhabditis elegans

Alignment Length:	462	Identity:	107/462 - (23%)
Similarity:	199/462 - (43%)	Gaps:	55/462 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GAFCLGAVIGWSGPVENEVKNSNAYNFTPR----------QTEWGLVGSLMTLGAAFSCIPVGVL 70
            |:|..|..:..:.|.:....|........|          |..|..|.:::.|||......:.::
Worm    20 GSFHFGFNLVLTNPSQEAFLNFMNQTLAKRFDGGLSDNTLQNIWSFVVAILFLGALAGSFSIRLI 84

  Fly    71 IGKIGRKTTMLILLPPFFIGWLLILLASHIAML---LLGRFVVGFCGGAFCVTCPMYVTEIAQVQ 132
            ...||||..:.|.:....:...:.:.:..|.:.   :..|.|:|:..........::::|.:..|
Worm    85 ADWIGRKNGLYISIAVGVLAGGMSIASKFIPLFELYIASRIVMGWSVSVSLGLSALFLSEASPKQ 149

  Fly   133 YRGTMGCFFQLLIVFGILYAFVVG-----GFVKTFYFNIACAILPVIFF-VLMIFMPESPIFLAQ 191
            .||.:|......:..|.:...|:.     |....::...|..|..::|| ..:.|.||||.||.|
Worm   150 NRGAIGMMTGTCVQLGTVCGSVIAMPQIFGTEDLWWLIYATEIGIMLFFGAALPFFPESPGFLIQ 214

  Fly   192 KGKAEKAEKSLKFLRGKDADVS----GELKEMSAEGQK--------------EKASVGKILCRRI 238
            :|..|.|.||:.:....:.|.:    .|:||......|              :||.:|.::...:
Worm   215 RGATEAATKSIAYYYNCEIDEAEKHLNEIKEEQKNSTKNFKMMDIVRKKSLRDKAFIGVVVTFAM 279

  Fly   239 TLKGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIATIISILVIEKV 303
            :..|:.:            |||..|  ..:.:|....||..::...:.:|..|::|::.:::::.
Worm   280 SFSGVAV------------INAFAF--DILKDTGLKVLEASLANDAISVVSMISSIVAAVIVDRN 330

  Fly   304 GRKILLLVS-ACMMGISTLIMALYFGMLMKSG--VGWLALIAVCVFIIGFSLGFGPVPWLMMAEL 365
            ||:.|||:| |.::..:.:|.||.|.......  :|::.:..:|:|...|:||.||:.:.:.|||
Worm   331 GRRPLLLISFAGILVCNLIIFALMFTFYKFENHVLGFILICFICIFTFFFALGPGPLCYFINAEL 395

  Fly   366 FAEDVKALAGSIAGTTNWCFAF-IVTLLFPVLNDIIGATACFAIFFGFAVAAFVFILFLIPETKG 429
            ..:..::.|.|.|........| |||...|:.|.:..|.:...:|.....|:.|::.|.:||||.
Worm   396 VGQAARSAAQSWASVIQMLSRFVIVTAFLPMKNQLGEAWSYLILFVAPVAASLVYLYFSLPETKN 460

  Fly   430 KTLNEIQ 436
            |...|::
Worm   461 KNPFEVE 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	107/460 (23%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	94/407 (23%)
C35A11.4	NP_504430.2	MFS_GLUT_Class1_2_like	13..461	CDD:340915	105/454 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157912
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850