DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and Slc2a13

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	NP_598295.2	Gene:	Slc2a13 / 171147	RGDID:	621814	Length:	637	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	133/536 - (24%)
Similarity:	223/536 - (41%)	Gaps:	129/536 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ALGAFCLGAVIGWSGPVENEVKNSNAYNFTPRQTE----W------GLVGSLMTLGAAFSCIPVG 68
            |||.|..|...|         ..|.|.....||..    |      |.||:     ||.:.:..|
  Rat    78 ALGGFLFGYDTG---------VVSGAMLLLRRQMRLGAMWQELLVSGAVGA-----AAVAALAGG 128

  Fly    69 VLIGKIGRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVTEIAQVQY 133
            .|.|.:||::.:|:......:|..::..|::...||.||.|||...|...:|.|:|:.|::....
  Rat   129 ALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNL 193

  Fly   134 RGTMGCFFQLLIVFGILYAFVVGGFVK-----TFYFNIACAILP-VIFFVLMIFMPESPIFLAQK 192
            ||.:.....|.|..|..:|.||.|...     .:.:.:..|.:| ||.|:..:|:||||.:|.||
  Rat   194 RGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQK 258

  Fly   193 GKAEKAEKSLKFLRGKDA--DVSGELKEMSAEGQKEKASVGKILCRRI----TLKGLFLSIGLML 251
            |:.:||.:.|..:||...  :....::....|.:||.::.|.|:||.:    |.:.|.:..||.:
  Rat   259 GQTQKARRILSQMRGNQTIDEEYDSIRNSIEEEEKEASAAGPIICRMLSYPPTRRALAVGCGLQM 323

  Fly   252 FQQMTGINAIIFYSTFIFETAGSTLEPRIS---TIIVGIVQAIATIISILVIEKVGRKILLLVSA 313
            |||::|||.|::||..|.:.:| ..:.|::   ..|......|.|::.:.::|||||:.|...|.
  Rat   324 FQQLSGINTIMYYSATILQMSG-VEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSL 387

  Fly   314 CMMGISTLIMALYFGMLMKSGV------------------------------------------- 335
            ....::..|:||  |.|:.:.|
  Rat   388 AGTTVALTILAL--GFLLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYKINSSA 450

  Fly   336 --------------------------------------------GWLALIAVCVFIIGFSLGFGP 356
                                                        .|.||:.:.::::.|:.|.||
  Rat   451 VIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSFCPTPYSWTALVGLVLYLVFFAPGMGP 515

  Fly   357 VPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVFIL 421
            :||.:.:|::....::...:.:...||.|..:|:|.|....:.:.....|.::.|||....:|:.
  Rat   516 MPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVY 580

  Fly   422 FLIPETKGKTLNEIQA 437
            ..:||||||.|.||::
  Rat   581 GCLPETKGKKLEEIES 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	132/533 (25%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	114/488 (23%)
Slc2a13	NP_598295.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	16..38
		MFS	75..580	CDD:119392	124/518 (24%)
		Sugar_tr	78..598	CDD:278511	133/536 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337690
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D524131at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750