Protein Alignment sut4 and SLC2A12

DIOPT Version :9

• Sequence 1: NP_523675.1
• Gene: sut4 / 36055
• FlyBaseID: FBgn0028560
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_660159.1
• Gene: SLC2A12 / 154091
• HGNCID: 18067
• Length: 617
• Species: Homo sapiens
• Alignment Length: 536
• Identity: 125/536 - (23%)
• Similarity: 245/536 - (45%)
• Gaps: 115/536 - (21%)

  Fly    11 FIGALGAFCLGAVIGW-----SGPVENEVKNSNAYNFTPRQTEWGLVGSLMTLGAAFSCIPVGVL 70
            |:.::.|...|.::|:     ||.: .::|...|.:...::    :|.|.:.:||..:.:..|||
Human    41 FLSSVTAAVSGLLVGYELGIISGAL-LQIKTLLALSCHEQE----MVVSSLVIGALLASLTGGVL 100

  Fly    71 IGKIGRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVTEIAQVQYRG 135
            |.:.||:|.:::......:|.|:::|:....:|::||..:|.......:...:|:.|||....||
Human   101 IDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRG 165

  Fly   136 TMGCFFQLLIVFGILYAFVVG-GFVKTFY-----FNIACAILP--VIFFVLMIFMPESPIFLAQK 192
            .:....:|:||.|||.|::.. .|...|:     |.:   ::|  |:..:.|.|:|.||.||..|
Human   166 LLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGL---VIPLGVLQAIAMYFLPPSPRFLVMK 227

  Fly   193 GKAEKAEKSLKFLRGKDADVSGELKEMSAEGQKE-KASVGKILCRRITLK-GLFLSIGLMLFQQM 255
            |:...|.|.|..||.. :|.:.||..:.:..:.| :.|...:...:..:: .:.:.:.|:.|.|:
Human   228 GQEGAASKVLGRLRAL-SDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQI 291

  Fly   256 TGINAIIFYSTFIFETAG--STLEPRISTIIVGIVQAIATIISILVIEKVGRKILLLVSACMMGI 318
            ||...|:||::.:.::.|  |.....:::..||:|:.|:||.:.|:::.||.|..|.:.:.:|..
Human   292 TGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAA 356

  Fly   319 STLIMAL-------------------------------------------YF------------- 327
            |.:.|.:                                           :|
Human   357 SLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMP 421

  Fly   328 -------------GMLMKSGVG------------------WLALIAVCVFIIGFSLGFGPVPWLM 361
                         ..|:.:|:.                  ||:|.::.|::..||:|.||:|||:
Human   422 LRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLV 486

  Fly   362 MAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGAT-ACFAIFFGFAVAAFVFILFLIP 425
            ::|:|...::..|.::..:.||....:::|.|..:.|:||.. .|| |:...::|:.:|::..||
Human   487 LSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCF-IYTIMSLASLLFVVMFIP 550

  Fly   426 ETKGKTLNEIQAKMGE 441
            ||||.:|.:|..::.:
Human   551 ETKGCSLEQISMELAK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	124/529 (23%)
		MFS	47..424	CDD:119392	109/476 (23%)
SLC2A12	NP_660159.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Sugar_tr	44..561	CDD:306568	123/526 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143936
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750