Protein Alignment sut4 and SLC2A13

DIOPT Version :10

• Sequence 1: NP_523675.1
• Gene: sut4 / 36055
• FlyBaseID: FBgn0028560
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_443117.3
• Gene: SLC2A13 / 114134
• HGNCID: 15956
• Length: 648
• Species: Homo sapiens
• Alignment Length: 538
• Identity: 140/538 - (26%)
• Similarity: 226/538 - (42%)
• Gaps: 119/538 - (22%)

  Fly     7 FIVGFIGALGAFCLGAVIGWSGPVENEVKNSNAYNFTPRQTE----WG--LVGSLMTLG-AAFSC 64
            ::|....|||.|..|...|         ..|.|.....||..    |.  ||.|  |:| ||.|.
Human    82 YVVAVFSALGGFLFGYDTG---------VVSGAMLLLKRQLSLDALWQELLVSS--TVGAAAVSA 135

  Fly    65 IPVGVLIGKIGRKTTMLILLPPFFIGWLLILLASHIAMLLLGRFVVGFCGGAFCVTCPMYVTEIA 129
            :..|.|.|..||:..:|:....|..|..::..|::...||.||.|||...|...:|.|:|:.|::
Human   136 LAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVS 200

  Fly   130 QVQYRGTMGCFFQLLIVFGILYAFVVGGFVK-----TFYFNIACAILP-VIFFVLMIFMPESPIF 188
            ....||.:.....|.|..|..:|.||.|...     .:.:.:..|.:| ||.|...:|:||||.:
Human   201 PPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRW 265

  Fly   189 LAQKGKAEKAEKSLKFLRGKDA--DVSGELKEMSAEGQKEKASVGKILCRRI----TLKGLFLSI 247
            |.|||:.:||.:.|..:||...  :....:|....|.:||..|.|.::||.:    |.:.|.:..
Human   266 LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGC 330

  Fly   248 GLMLFQQMTGINAIIFYSTFIFETAGSTLEPRIS---TIIVGIVQAIATIISILVIEKVGRKILL 309
            ||.:|||::|||.|::||..|.:.:| ..:.|::   ..:......|.|::.:.::|||||:.|.
Human   331 GLQMFQQLSGINTIMYYSATILQMSG-VEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLT 394

  Fly   310 LVSACMMGISTLIMALYFGM------------------------------------------LMK 332
            ..|.....::.:|:||.|.:                                          :.|
Human   395 FGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNK 459

  Fly   333 SGV-------------------------------------------GWLALIAVCVFIIGFSLGF 354
            |.|                                           .|.||:.:.::::.|:.|.
Human   460 STVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGM 524

  Fly   355 GPVPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVF 419
            ||:||.:.:|::....::...:.:...||.|..:|:|.|....:.:.....|.::.|||....:|
Human   525 GPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLF 589

  Fly   420 ILFLIPETKGKTLNEIQA 437
            |...:||||||.|.||::
Human   590 IYGCLPETKGKKLEEIES 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	MFS_GLUT6_8_Class3_like	7..434	CDD:340916	138/533 (26%)
SLC2A13	NP_443117.3	MFS_HMIT_like	87..596	CDD:340918	130/520 (25%)