DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sut4 and slc2a4

DIOPT Version :9

Sequence 1:	NP_523675.1	Gene:	sut4 / 36055	FlyBaseID:	FBgn0028560	Length:	444	Species:	Drosophila melanogaster
Sequence 2:	XP_031755513.1	Gene:	slc2a4 / 101731550	XenbaseID:	XB-GENE-5943313	Length:	509	Species:	Xenopus tropicalis

Alignment Length:	471	Identity:	153/471 - (32%)
Similarity:	240/471 - (50%)	Gaps:	51/471 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TATQFIVGFIGALGAFCLGAVIGWSGPVENEVKNSNAYNFTPR-------------QTEWGLVGS 54
            |.|..:..|...||:|..|..||.....:..::.|...::..|             :|.|.|..:
Frog    21 TKTLVLSVFTAILGSFQFGYNIGVINAPQKIIEQSYNESWISRSSSGSASIDPGLLRTLWSLSVA 85

  Fly    55 LMTLGAAFSCIPVGVLIGKIGRKTTMLI-----LLPPFFIGWLLILLASHIAMLLLGRFVVGFCG 114
            :.::|...|.:.|||:...:|||..|:|     .|...|:|  |..:.....|:::|||::|...
Frog    86 IFSIGGMVSSLSVGVVSQWLGRKRAMVINNVFAFLAGSFMG--LSQVCQSYEMMIVGRFLIGVYS 148

  Fly   115 GAFCVTCPMYVTEIAQVQYRGTMGCFFQLLIVFGILYAFVVG--GFVKTFYFNIACAILPVIFFV 177
            |......||||.||:....||.||...||.:|.|||.|.|:|  .|:.|   |..   .|.:|:|
Frog   149 GLASGLVPMYVGEISPTHLRGAMGTLHQLSLVIGILVAQVLGLELFLGT---NTR---WPALFWV 207

  Fly   178 LMI----------FMPESPIFLAQKGKAE-KAEKSLKFLRGKDADVSGELKEMSAE----GQKEK 227
            .:|          |.||||.||....:.| :|:|||:.|.|. .||:.:|.:|..|    ..:.|
Frog   208 TLIPAALQCLMLPFCPESPRFLYIVCEQEAQAKKSLRRLTGL-PDVTDDLSDMKEEKRQMDSEPK 271

  Fly   228 ASVGKILCRRITLKGLFLSIGLMLFQQMTGINAIIFYSTFIFETAGSTLEPRISTIIVGIVQAIA 292
            .|:.:|...|...:.:.::|.|.|.||::|||||.:|||.||..|| ..:|..:||..|||....
Frog   272 VSILQIFRSRNYRQPILVAIVLQLSQQLSGINAIFYYSTDIFSKAG-VEQPIYATIGAGIVNTAF 335

  Fly   293 TIISILVIEKVGRKILLLVSACMMGISTLIMALYFGMLMKSGV---GWLALIAVCVFIIGFSLGF 354
            |::|:.::|:.||:.|.|:....|.:..|:|..  .|:::..|   .:|::.|:..|:..|.:|.
Frog   336 TVVSLFLVERAGRRTLQLLGLAGMIVCALLMTA--AMVLQESVPSLSYLSMAAIFGFVAFFEIGP 398

  Fly   355 GPVPWLMMAELFAEDVKALAGSIAGTTNWCFAFIVTLLFPVLNDIIGATACFAIFFGFAVAAFVF 419
            ||:||.::||||::..:..|.:|||.|||...||:.:.|..:.::.|... |.:|.....|..:|
Frog   399 GPIPWFIVAELFSQGPRPAAMAIAGCTNWTSNFIIGMGFQYVAELCGPYV-FLLFGALLFAFLIF 462

  Fly   420 ILFLIPETKGKTLNEI 435
            ..|.:|||:|::.:||
Frog   463 TYFRVPETRGRSFDEI 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sut4	NP_523675.1	Sugar_tr	9..436	CDD:278511	151/465 (32%)
sut4	NP_523675.1	MFS	47..424	CDD:119392	136/401 (34%)
slc2a4	XP_031755513.1	MFS_GLUT_Class1	26..473	CDD:340989	148/459 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010