Protein Alignment egr and TNFSF12

DIOPT Version :9

• Sequence 1: NP_724878.2
• Gene: egr / 36054
• FlyBaseID: FBgn0033483
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_003800.1
• Gene: TNFSF12 / 8742
• HGNCID: 11927
• Length: 249
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 57/227 - (25%)
• Similarity: 89/227 - (39%)
• Gaps: 44/227 - (19%)

  Fly   208 RKSRSIADVRNEEQNIQGNHTELQEKSSNEATSKES--PAPLHHRRRMHSRHRHLLVRKGESLLS 270
            |.|.|..:...||...:    |.|:.|.....::||  |||..:|          |||...|...
Human    47 RASLSAQEPAQEELVAE----EDQDPSELNPQTEESQDPAPFLNR----------LVRPRRSAPK 97

  Fly   271 ARSEDSRP--AAHFHLSSRRRHQGSM-GYHGDMYIGNDNERNSYQG-HFQTRDGVLTVTNTGLYY 331
            .|...:|.  |||:.:..|....|:. |..|.:....:...||... .:..:.|...||..||||
Human    98 GRKTRARRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYY 162

  Fly   332 VYAQICYNNSHDQNGFIVF------QGDTPFLQCLN----TVPTNMPHKVHTCHTSGLIHLERNE 386
            :|.|:     |...|..|:      ......|:||.    |..:::..::..|..|||:.|....
Human   163 LYCQV-----HFDEGKAVYLKLDLLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGS 222

  Fly   387 RIHLKDI---HNDRNAVLREGNNRSYFGIFKV 415
            .:.::.:   |      |:.....:|||:|:|
Human   223 SLRIRTLPWAH------LKAAPFLTYFGLFQV 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
egr	NP_724878.2	TNF	278..413	CDD:238108	35/151 (23%)
TNFSF12	NP_003800.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	55..85		10/33 (30%)
		TNF	131..248	CDD:214557	29/127 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15151
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10146
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.040