Protein Alignment egr and TNFSF13

DIOPT Version :10

• Sequence 1: NP_724878.2
• Gene: egr / 36054
• FlyBaseID: FBgn0033483
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_003799.1
• Gene: TNFSF13 / 8741
• HGNCID: 11928
• Length: 250
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 42/207 - (20%)
• Similarity: 82/207 - (39%)
• Gaps: 71/207 - (34%)

  Fly   213 IADVRNEEQNIQGN-----------HTELQEKSS-------NEATSKESPAPLHHRRRMHSRHRH 259
            :..:|.|...:||.           ...|.|:||       |...|::..|.|..:::......|
Human    55 LQSLRREVSRLQGTGGPSQNGEGYPWQSLPEQSSDALEAWENGERSRKRRAVLTQKQKKQHSVLH 119

  Fly   260 LLVRKGESLLSARSEDS--------RPAAHFHLSSRRRHQG--SMGYHGDMYIGNDNERNSYQGH 314
            |:.      ::|.|:|.        :||.       ||.:|  :.||
Human   120 LVP------INATSKDDSDVTEVMWQPAL-------RRGRGLQAQGY------------------ 153

  Fly   315 FQTRDGVLTVTNTGLYYVYAQICYNNSHDQNGFIVF---QG--DTPFLQCLNTVPTNMPHKVHTC 374
                 || .:.:.|:|.:|:|:.:.:.....|.:|.   ||  :|.| :|:.::|::.....::|
Human   154 -----GV-RIQDAGVYLLYSQVLFQDVTFTMGQVVSREGQGRQETLF-RCIRSMPSHPDRAYNSC 211

  Fly   375 HTSGLIHLERNE 386
            :::|:.||.:.:
Human   212 YSAGVFHLHQGD 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
egr	NP_724878.2	TNF	278..413	CDD:238108	25/116 (22%)
TNFSF13	NP_003799.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..82		3/20 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..108		3/18 (17%)
		TNF	117..248	CDD:238108	30/145 (21%)