Protein Alignment egr and Tnfsf12

DIOPT Version :10

• Sequence 1: NP_724878.2
• Gene: egr / 36054
• FlyBaseID: FBgn0033483
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: XP_006246807.1
• Gene: Tnfsf12 / 360548
• RGDID: 1359620
• Length: 250
• Species: Rattus norvegicus
• Alignment Length: 211
• Identity: 49/211 - (23%)
• Similarity: 86/211 - (40%)
• Gaps: 41/211 - (19%)

  Fly   231 QEKSSNEATSKESPAPLH-HRRRMHSR----HRHLLVRKGESLLSARSEDSRP----AAHFHLSS 286
            ||.|..|.|:::...|.. :.:.:.|:    ....|||...|:...|.  :||    |||:.:..
  Rat    54 QEPSQEELTAEDHREPPELNPQTVESQDVVPFLEQLVRPRRSVSKGRK--ARPRRAIAAHYEVHP 116

  Fly   287 RRRHQGSM-GYHGDMYIGNDNERNSYQG-HFQTRDGVLTVTNTGLYYVYAQICYNNSHD------ 343
            :....|:. |..|.:....:.:.||... .:..:.|..||...||||:|.|:.::....
  Rat   117 QPGQDGAQAGVDGTVSGWEETKINSSSPLRYDRQIGEFTVIRAGLYYLYCQVHFDEGKAVYLKLD 181

  Fly   344 --QNGFIVFQGDTPFLQCLN----TVPTNMPHKVHTCHTSGLIHLERNERIHLKDI---HNDRNA 399
              .||.:.       |:||.    |..::...::..|..|||:.|.....:.::.:   |
  Rat   182 LLVNGVLA-------LRCLEEFSATAASSPGPQLRLCQVSGLLPLRPGSSLRIRTLPWAH----- 234

  Fly   400 VLREGNNRSYFGIFKV 415
             |:.....:|||:|:|
  Rat   235 -LKAAPFLTYFGLFQV 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
egr	NP_724878.2	TNF	278..413	CDD:238108	34/155 (22%)
Tnfsf12	XP_006246807.1	TNF	132..249	CDD:214557	28/129 (22%)