Protein Alignment CG1371 and Nomo1

DIOPT Version :10

• Sequence 1: NP_610551.1
• Gene: CG1371 / 36053
• FlyBaseID: FBgn0033482
• Length: 1199
• Species: Drosophila melanogaster
• Sequence 2: XP_006229170.1
• Gene: Nomo1 / 361578
• RGDID: 1305240
• Length: 1230
• Species: Rattus norvegicus
• Alignment Length: 1273
• Identity: 397/1273 - (31%)
• Similarity: 620/1273 - (48%)
• Gaps: 156/1273 - (12%)

  Fly     5 SGVFVILLIKLFQNANAGEVEVVGCGGFIKSHAEIDFSRVEIKLLTKQGSLKDKTDCSPSNGYYF 69
            :.|.::||:.....|...|..|||||||:||..||::|.:||||.||.|:||.:|||:|:|||:.
  Rat     7 AAVLLLLLLSGPGRAIGSEDIVVGCGGFVKSDVEINYSLIEIKLYTKHGTLKYQTDCAPNNGYFM 71

  Fly    70 LPIYDKGDYLLSISPPPGWSFEPEQVELNFDGKTDVCSQGRDVNFVFKGFGITGQVALAAGG--G 132
            :|:|||||::|.|.||.||||||..|||:.||.:|||::|.|:||||.||.:.|:| |:.|.  |
  Rat    72 IPLYDKGDFILKIEPPLGWSFEPTNVELHVDGVSDVCTRGGDINFVFTGFSVNGKV-LSKGQPLG 135

  Fly   133 ARGVDVELRS--EQGEVRRTKSDANGVFSFTPIIPGNYVVKASHARWHFSKAEHKVVVVSGNTEL 195
            ..||.|.|||  ...:::.|.:...|.|:|..::||:|.:.|:|..|...:|...|.|.:.|..
  Rat   136 PAGVQVSLRSTGADSKIQSTVTQPGGKFAFFKVLPGDYEILATHPTWALKEASTTVRVTNSNAN- 199

  Fly   196 PANSLVVSGFDVVGRFDS-SSPLPGNLGVALYKKKGQSLVPK-----CETSSPA---PPNSVNSA 251
            .|..|:|:|::|.|...| ..|:.| :...|:    .|||.|     |..|..:   ||:
  Rat   200 AAGPLIVAGYNVSGSVRSDGEPMKG-VKFLLF----SSLVNKEDVLGCNVSPVSGFQPPD----- 254

  Fly   252 YES-ASSCFSQLDKSGEYIFKNVPSGKYLLQAINLDSKLKLHLSPELLELEVGKDTLQIKDEFKI 315
             || ...|::...:.|.:.|.::|||.|.:.......::...::|..|:..|..|:|:|:..|.:
  Rat   255 -ESLVYLCYAVSKEDGSFSFYSLPSGGYTVVPFYRGERITFDVAPSRLDFTVEHDSLRIEPVFHV 318

  Fly   316 TGFTVSGRVLTSAGGEPLKSAVIKVNGKKVAETDAQGSYTLENLKAGTVNIEVESSQLQFSPLQV 380
            .||:|:||||....||.:..||:.:|.:....|.|.||:.|||:..||..|..:...|.|..:.:
  Rat   319 MGFSVTGRVLNGPDGEGVPEAVVTLNNQIKVRTKADGSFRLENITTGTYTIHAQKEHLYFDMVTI 383

  Fly   381 KAQINTASLPTIVPSAYEVCGKVV---SP---KSHNVGLTKIGSTFHSSASTNAET---GNWCAF 436
            |...||..|..::.:.:.:||::.   ||   |..|.....:.|.....|....||   |::|..
  Rat   384 KIAPNTPQLADLIATGFSICGQISIIRSPDTIKQMNKYKVVLSSQDKDKALVTVETDAHGSFCFK 448

  Fly   437 LPVGKYTIEVLTTDADKAAGVQFFPVQQQTEVRDAPVNGITFSQLRAKIRGELQCLPDATATCTS 501
            ...|.|.::|:..:|:..||:...|......|.:.||..:.|.|..|.:.|::.||.    ||..
  Rat   449 AKPGIYKVQVVVPEAETRAGLMLKPQTFPITVTNKPVMDVAFVQFLASVSGKVSCLD----TCGD 509

  Fly   502 AEVTLQALDATGQPTENKWKARAHRGKYVFKDMLPGPYELTIPQGNLCYESTRVFLNVASAEEDA 566
            ..||||:|...|:....:...:.:...:.|..:|||.|:::|...:.|:.:..:.:.|...:..|
  Rat   510 LLVTLQSLSRQGEKRSLQLSGKVNSMTFTFDKVLPGKYKISIMHEDWCWRNKSLEVEVLEDDVSA 574

  Fly   567 PPFVHKGYEVSIISSHRALMKYTHVTGPSEPKAPTESLKIASGVNTFCVKKYGSYDFKLEGCH-- 629
            ..|...||.:....||...::: |..|.........:|  :.|||.||:.|.|.|......||
  Rat   575 VEFRQTGYMLRCALSHAITLEF-HQDGNGPENVGIYNL--SRGVNRFCLSKPGVYKVTPRSCHRF 636

  Fly   630 -----TYDESLPSKFITPEPDQLQTLIINAVAHKTGVRVLSTEPTAD---SIKLVLESESL---- 682
                 |||.|.||           .|.:.|:.|.. :..:.|:...|   :||..::||..
  Rat   637 EQAFYTYDTSSPS-----------ILTLTAIRHHV-LGTIITDKMMDVTVTIKSSIDSEPALVLG 689

  Fly   683 ----------------------------------------GQEVITPVAESHKVDGKFAYRYDTY 707
                                                    |||::      .::.|.|:|.:..:
  Rat   690 PLKSAQELRREQQLAEIETRRQEREKNGKEEGEEGRARPPGQEMV------DELQGPFSYDFSYW 748

  Fly   708 LKPEQVLRITPVSDVLLFAPQQHE-IVGSSDCVDIAFNFVATRGLILRGKVVPAIKDAKITLSFP 771
            .:..:.:.:||.|..|||.|...| .|....|...........||.|.|::.|.::..:|.:|
  Rat   749 ARCGEKITVTPSSKELLFYPPSMEATVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVIS-- 811

  Fly   772 DQPELES--LEVLTSVTGEFKFGPIEESLAFDLKAEKESYVFSDYNRQTASFSAHKLCEISVVVK 834
             :....|  :.|.|...|.:..||:...|.:.:.::||.:|.:........|.|:.|..:|..:|
  Rat   812 -EKGASSPLITVFTDDKGAYSVGPLHSDLEYTVTSQKEGFVLTAVEGTVGDFKAYALAGVSFEIK 875

  Fly   835 DEAGQTLGGVLLSLSGGESYRKNLVTGDNGAINFHSLSPSQYYLRPMMKEYKFEPNSKMIDIKDG 899
            .|..|.|.||||||||| .:|.||:|.|||.:.|.:|||.|||.:|||||::|||:|:||::::|
  Rat   876 AEDDQPLPGVLLSLSGG-VFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEG 939

  Fly   900 ETVSVTLVGKRFAYSIFGTVSSLNGDPFAGVNVQATADNSCPQQPEEATSEANGQYRIRGLQPGC 964
            :.:.:|:.|.|.|||.:||||||||:|..||.|:|.....|....|:..::..|::|:|||.|||
  Rat   940 QNLRITITGFRTAYSCYGTVSSLNGEPEQGVAVEAVGQKDCSIYGEDTVTDEEGKFRLRGLLPGC 1004

  Fly   965 SYSVRVVPD-KEIVERSIPAQHTVKVANEDVRDINLVAISPLKIVDITARVTATLNEHYKTLRIV 1028
            .|.|::..: .:.:||::|....::|.|.||.|:|::....:...|::..| .|.:|:..||.:.
  Rat  1005 MYHVQLKAEGNDHIERALPHHRVIEVGNNDVDDVNIIVFRQINQFDLSGNV-ITSSEYLSTLWVK 1068

  Fly  1029 MYRKGNSDSPVFSQRVGTPVNPKARLNPGITVFFPRIPLDGKSYVVELQSTLSDKTYTYKLPSTT 1093
            :|:..:.|:|:  |.|.        |...:...||.:..||::|||.|.|||....|.|.||..:
  Rat  1069 LYKSESLDNPI--QTVS--------LGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYVLPQVS 1123

  Fly  1094 FVADRGSVFVELEFKP----------------EVRAAEADLNQNSISALVLIALVAIAFFKQDLA 1142
            |.|......:.|.|.|                :.:..|.|:.|.|..||.|..|:.:|.:..|..
  Rat  1124 FAAVGYHKHITLVFSPTWSMSENLQGVTAIPLQRKLPEQDIAQGSYIALPLTLLLLLAGYNHDKL 1188

  Fly  1143 TSFLSFVWSKLNDV------AADLAQRQKSKTQVRKNE 1174
            ...|..:.|:|..|      |:|.:..:..|.|.:|.:
  Rat  1189 IPLLLQLTSRLQGVRALGQAASDSSGPEDMKRQTKKQK 1226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1371	NP_610551.1	ClfA	<44..456	CDD:443959	151/434 (35%)
		ClfA	<828..>969	CDD:443959	70/140 (50%)
		CarboxypepD_reg	914..>970	CDD:433354	26/55 (47%)
Nomo1	XP_006229170.1	ClfA	94..>548	CDD:443959	144/470 (31%)
		ClfA	<803..>1003	CDD:443959	81/203 (40%)