Protein Alignment CG1371 and Nomo1

DIOPT Version :10

• Sequence 1: NP_610551.1
• Gene: CG1371 / 36053
• FlyBaseID: FBgn0033482
• Length: 1199
• Species: Drosophila melanogaster
• Sequence 2: NP_694697.3
• Gene: Nomo1 / 211548
• MGIID: 2385850
• Length: 1214
• Species: Mus musculus
• Alignment Length: 1266
• Identity: 391/1266 - (30%)
• Similarity: 617/1266 - (48%)
• Gaps: 158/1266 - (12%)

  Fly     5 SGVFVILLIKLFQNANAGEVEVVGCGGFIKSHAEIDFSRVEIKLLTKQGSLKDKTDCSPSNGYYF 69
            :...::||:.....|...|..|||||||:||..||::|.:||||.||.|:||.:|||:|:|||:.
Mouse     7 AAALLLLLLSGAGRAIGSEDIVVGCGGFVKSDVEINYSLIEIKLYTKHGTLKYQTDCAPNNGYFM 71

  Fly    70 LPIYDKGDYLLSISPPPGWSFEPEQVELNFDGKTDVCSQGRDVNFVFKGFGITGQVALAAGG--G 132
            :|:|||||::|.|.||.||||||..|||..||.:|:|::|.|:||:|.||.:.|:| |:.|.  |
Mouse    72 IPLYDKGDFILKIEPPLGWSFEPTNVELRVDGVSDICTKGGDINFLFTGFSVNGKV-LSKGQPLG 135

  Fly   133 ARGVDVELRS--EQGEVRRTKSDANGVFSFTPIIPGNYVVKASHARWHFSKAEHKVVVVSGNTEL 195
            ..||.|.|||  ...:::.|.:...|.|:|..::||:|.:.|:|..|...:|...|.|.:.|..
Mouse   136 PAGVQVSLRSTGADSKIQSTVTQPGGKFAFFKVLPGDYEILATHPTWALKEASTTVRVTNSNAN- 199

  Fly   196 PANSLVVSGFDVVGRFDS-SSPLPGNLGVALYKKKGQSLVPK-----CETSSPA---PPNSVNSA 251
            .|..|:|:|::|.|...| ..|:.| :...|:    .|||.|     |..|..:   ||:
Mouse   200 AAGPLIVAGYNVSGSVRSDGEPMKG-VKFLLF----SSLVNKEDVLGCNVSPVSGFQPPD----- 254

  Fly   252 YES-ASSCFSQLDKSGEYIFKNVPSGKYLLQAINLDSKLKLHLSPELLELEVGKDTLQIKDEFKI 315
             || ...|::...:.|.:.|.::|||.|.:.......::...::|..|:..|..|:|:|:..|.:
Mouse   255 -ESLVYLCYAVSKEDGSFSFYSLPSGGYTVVPFYRGERITFDVAPSRLDFTVEHDSLRIEPVFHV 318

  Fly   316 TGFTVSGRVLTSAGGEPLKSAVIKVNGKKVAETDAQGSYTLENLKAGTVNIEVESSQLQFSPLQV 380
            .||:|:||||....||.:..||:.:|.:...:|.|.||:.|||:..||..|..:...|.|..:.:
Mouse   319 MGFSVTGRVLNGPDGEGVPEAVVTLNNQIKVKTKADGSFRLENITTGTYTIHAQKEHLYFEMVTI 383

  Fly   381 KAQINTASLPTIVPSAYEVCGK------------------VVSPKSHNVGLTKIGSTFHSSASTN 427
            |...||..|..::.:.:.:||:                  |:|.:..:..|..:.|..|
Mouse   384 KIAPNTPQLADLIATGFSICGQIAIVRSPDTIKQMSKYRVVLSSQDKDKALLTVDSDAH------ 442

  Fly   428 AETGNWCAFLPVGKYTIEVLTTDADKAAGVQFFPVQQQTEVRDAPVNGITFSQLRAKIRGELQCL 492
               |::|.....|.|.::|:..:|:..||:...|......|.:.||..:.|.|..|.:.|::.||
Mouse   443 ---GSFCFKAKPGAYKVQVVVPEAETRAGLMLKPQVFPLTVTNRPVMDVAFVQFLASVSGKVSCL 504

  Fly   493 PDATATCTSAEVTLQALDATGQPTENKWKARAHRGKYVFKDMLPGPYELTIPQGNLCYESTRVFL 557
            .    ||....||||:|...|:....:...:.:...:.|..:|||.|:::|...:.|:.:..:.:
Mouse   505 D----TCGDLLVTLQSLSRQGEKRSLQLSGKVNSMTFTFDKVLPGRYKISIMHEDWCWRNKSLEV 565

  Fly   558 NVASAEEDAPPFVHKGYEVSIISSHRALMKYTHVTGPSEPKAPTESLKIASGVNTFCVKKYGSYD 622
            .|...:..|..|...||.:....||...::: |..|.........:|  :.|||.||:.|.|.|.
Mouse   566 EVLEDDVSAVEFRQTGYMLRCALSHAITLEF-HQDGNGPENVGIYNL--SRGVNRFCLSKPGVYK 627

  Fly   623 FKLEGCH-------TYDESLPSKFITPEPDQLQTLIINAVAHKTGVRVLSTEPTAD---SIKLVL 677
            .....||       |||.|.||           .|.:.|:.|.. :..:.|:...|   :||..:
Mouse   628 VTPRSCHRFEQAFYTYDTSSPS-----------ILTLTAIRHHV-LGTIITDKMMDVTVTIKSSI 680

  Fly   678 ESESL--------------------------------------------GQEVITPVAESHKVDG 698
            :||..                                            |||::      .::.|
Mouse   681 DSEPALVLGPLKSAQELRREQQLAEIETRRQEREKNGKEEGEEGRARPPGQEMV------DELQG 739

  Fly   699 KFAYRYDTYLKPEQVLRITPVSDVLLFAPQQHE-IVGSSDCVDIAFNFVATRGLILRGKVVPAIK 762
            .|:|.:..:.:..:.:.:||.|..|||.|...| .|....|...........||.|.|::.|.::
Mouse   740 PFSYDFSYWARSGEKITVTPSSKELLFYPPSMEATVSGESCPGKLIEIHGKAGLFLEGQIHPELE 804

  Fly   763 DAKITLSFPDQPELES--LEVLTSVTGEFKFGPIEESLAFDLKAEKESYVFSDYNRQTASFSAHK 825
            ..:|.:|   :....|  :.|.|...|.:..||:...|.:.:.::||.||.:........|.|:.
Mouse   805 GVEIVIS---EKGASSPLITVFTDDKGAYSVGPLHSDLEYTVNSQKEGYVLTAVEGTVGDFKAYA 866

  Fly   826 LCEISVVVKDEAGQTLGGVLLSLSGGESYRKNLVTGDNGAINFHSLSPSQYYLRPMMKEYKFEPN 890
            |..:|..:|.|..|.|.||||||||| .:|.||:|.|||.:.|.:|||.|||.:|||||::|||:
Mouse   867 LAGVSFEIKAEDDQPLPGVLLSLSGG-VFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPS 930

  Fly   891 SKMIDIKDGETVSVTLVGKRFAYSIFGTVSSLNGDPFAGVNVQATADNSCPQQPEEATSEANGQY 955
            |:||::::|:.:.:|:.|.|.|||.:||||||||:|..||.|:|.....|....|:..::..|::
Mouse   931 SQMIEVQEGQNLRITITGFRTAYSCYGTVSSLNGEPEQGVAVEAVGQKDCSIYGEDTVTDEEGKF 995

  Fly   956 RIRGLQPGCSYSVRVVPD-KEIVERSIPAQHTVKVANEDVRDINLVAISPLKIVDITARVTATLN 1019
            |:|||.|||.|.|::..: .:.:||::|....::|.|.||.|:|::....:...|::..| .|.:
Mouse   996 RLRGLLPGCMYHVQLKAEGNDHIERALPHHRVIEVGNNDVDDVNIIVFRQINQFDLSGNV-ITSS 1059

  Fly  1020 EHYKTLRIVMYRKGNSDSPVFSQRVGTPVNPKARLNPGITVFFPRIPLDGKSYVVELQSTLSDKT 1084
            |:..||.:.:|:..:.|:|:  |.|.        |...:...||.:..||::|||.|.:||....
Mouse  1060 EYLSTLWVKLYKSESLDNPI--QTVS--------LGQSLFFHFPPLLRDGENYVVLLDTTLPRSQ 1114

  Fly  1085 YTYKLPSTTFVADRGSVFVELEFKPEVRAAEADLNQNSISALVLIALVAIAFFKQDLATSFLSFV 1149
            |.|.||..:|.|......:.|.|.|..:..|.|:.|.|..||.|..|:.:|.:..|.....|..:
Mouse  1115 YDYVLPQVSFTAVGYHKHITLVFSPTRKLPEQDIAQGSYIALPLTLLLLLAGYNHDKLIPLLLQL 1179

  Fly  1150 WSKLNDV------AADLAQRQKSKTQVRKNE 1174
            .|:|..|      |:|.:..:..|.|.:|.:
Mouse  1180 TSRLQGVRALGQAASDSSGPEDMKRQTKKQK 1210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1371	NP_610551.1	ClfA	<44..456	CDD:443959	146/443 (33%)
		ClfA	<828..>969	CDD:443959	70/140 (50%)
		CarboxypepD_reg	914..>970	CDD:433354	26/55 (47%)
Nomo1	NP_694697.3	ClfA	<47..>368	CDD:443959	126/333 (38%)
		ClfA	<330..>549	CDD:443959	59/231 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	708..733		2/24 (8%)
		ClfA	<803..>1003	CDD:443959	82/203 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1190..1214		5/21 (24%)