Protein Alignment Cdc2rk and cdk-11.2

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_509746.2
• Gene: cdk-11.2 / 181247
• WormBaseID: WBGene00013917
• Length: 668
• Species: Caenorhabditis elegans
• Alignment Length: 342
• Identity: 131/342 - (38%)
• Similarity: 216/342 - (63%)
• Gaps: 20/342 - (5%)

  Fly    36 MPIPEQNLFGRCRPVSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLRE 100
            :|:....|.| |:.:||:..||.:.||:||.|:|.::||::|:||||:.:|::||:|.||:.|||
 Worm   288 LPVYYPGLRG-CQHISEYVILNVIAEGTYGEVFRGKNTRTDEVVALKRFKMEKEKEGFPITALRE 351

  Fly   101 I-MILKQCHHENIVRLREVVVGKSLDSIFLVMDFCEQDLASVLDNM---SQPFTESEVKCITLQV 161
            | |:||...|||||.::|::||.:...:::.|::.|.|:.|::|.|   :|.|...:.|.:..|:
 Worm   352 INMLLKAGAHENIVNVKEILVGSTKTEVYMAMEYVEHDVKSLIDKMRSRNQRFKTGQQKTLMSQL 416

  Fly   162 LKALKYLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFS-----NPPKPMTPQMVTLWYRAP 221
            |..::::|..:::|||||.||||::..|.:|:|||||||.:.     .....:||.:||||||:|
 Worm   417 LSGIEHMHKLWILHRDLKTSNLLISHSGILKIADFGLAREYGEARDIEKRMKLTPIVVTLWYRSP 481

  Fly   222 ELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAV 286
            ||||..:|::|.||||:.|||:.|.::.||:..|:||..|:..|..::|.|:|.|||   |:..:
 Worm   482 ELLLEPKTYSTPVDMWSIGCIMAEFIMMKPMFQGDSEPNQVHQIFQMMGTPTEQIWP---DIKEL 543

  Fly   287 QNFTLSQQP------YNNLTPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKYFVDPPQACD 345
            :.:.:.:.|      ...:.....::.::|.:|||.:...||..|.||.|.|:..:|.:.|:|..
 Worm   544 KVWNMVEFPPVKPGQLRRIFKGEKLVNETGFDLLNGMLCLNPANRLTASEALQHDWFSEHPKAVP 608

  Fly   346 PGMMPTFP-QHRNNAAP 361
            |..:|.:| :...||||
 Worm   609 PEDLPVYPAKSELNAAP 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	124/322 (39%)
cdk-11.2	NP_509746.2	Protein Kinases, catalytic domain	298..600	CDD:473864	118/304 (39%)