Protein Alignment Cdc2rk and cdk-12

DIOPT Version :9

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_001367220.1
• Gene: cdk-12 / 175559
• WormBaseID: WBGene00007135
• Length: 734
• Species: Caenorhabditis elegans
• Alignment Length: 385
• Identity: 127/385 - (32%)
• Similarity: 209/385 - (54%)
• Gaps: 53/385 - (13%)

  Fly    13 PAPDPQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPV-----------------------SEFE 54
            |.|.||.    .|...|.....|:|:|..:.....|||                       :.:.
 Worm   252 PPPPPQT----DGGASSSKRQDPLPMPPDSKRIATRPVITTRRGHATNRPSDSDSWYKTNLTHYT 312

  Fly    55 KLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVV 119
            .|:::|||:||.||:|.:..:.|.||||:||::.||:|.||:.:|||.||:|.||:|||||.::|
 Worm   313 MLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAIREIKILRQLHHKNIVRLMDIV 377

  Fly   120 VGK-SLDSI-------FLVMDFCEQDLASVLDNMS-QPFTESEVKCITLQVLKALKYLHSRFMIH 175
            :.. |:|.:       :||.::.:.||..:|::.. ..|.:.::..:..|:|:.|.|:|:...:|
 Worm   378 IDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELVDFNKDQICSLFKQLLEGLAYIHNTGFLH 442

  Fly   176 RDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFG 240
            ||:|.||:|:.:||.:|:||.||||::....:..|.:::|||||.||||||...:..|:|:|:.|
 Worm   443 RDIKCSNILVNNKGELKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTG 507

  Fly   241 CILGELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKF-H 304
            |:||||...|||..||:|..||::|..:.|:|:...||...:|.....|.:.:.....:..:| |
 Worm   508 CMLGELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTELVGWNTFRMKRTYQRRIREEFEH 572

  Fly   305 MIGQSGRNLLNILFIYNPKTRATAEECLKSKYF-------VDPPQACDPGMMPTFPQHRN 357
            ::.:...:||:.:...||:.|.:|:|.|...:.       |.|.:         .|||::
 Worm   573 IMPREAVDLLDKMLTLNPEKRISAKEALNHPWIRSLEHTTVQPLK---------LPQHQD 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	115/347 (33%)
		S_TKc	53..337	CDD:214567	110/293 (38%)
cdk-12	NP_001367220.1	STKc_CDK12	303..605	CDD:270847	110/301 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920