Protein Alignment Cdc2rk and Cdk5

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_543161.1
• Gene: Cdk5 / 140908
• RGDID: 70514
• Length: 292
• Species: Rattus norvegicus
• Alignment Length: 304
• Identity: 130/304 - (42%)
• Similarity: 186/304 - (61%)
• Gaps: 24/304 - (7%)

  Fly    50 VSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVR 114
            :.::|||.::|||:||.|::|::..::||||||:||:|.:.:|:|.|.||||.:||:..|:||||
  Rat     1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVR 65

  Fly   115 LREVVVGKSLDSIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLK 179
            |.:|:  .|...:.||.:||:|||....|:.:.......||.:..|:||.|.:.|||.::|||||
  Rat    66 LHDVL--HSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSRNVLHRDLK 128

  Fly   180 VSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILG 244
            ..|||:...|.:|:|||||||.|..|.:..:.::||||||.|::|.|.:.::|::|||:.|||..
  Rat   129 PQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFA 193

  Fly   245 ELL-LGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYN---------NL 299
            ||. .|:||.|||....||..|..|||.|:|..||....||       ..:||.         |:
  Rat   194 ELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLP-------DYKPYPMYPATTSLVNV 251

  Fly   300 TPKFHMIGQSGRNLLNILFIYNPKTRATAEECLKSKYFVD--PP 341
            .||   :..:||:||..|...||..|.:|||.|:..||.|  ||
  Rat   252 VPK---LNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	130/304 (43%)
Cdk5	NP_543161.1	STKc_CDK5	3..286	CDD:143344	125/294 (43%)