Protein Alignment Cdc2rk and Cdk11b

DIOPT Version :9

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_031687.2
• Gene: Cdk11b / 12537
• MGIID: 88353
• Length: 784
• Species: Mus musculus
• Alignment Length: 365
• Identity: 174/365 - (47%)
• Similarity: 240/365 - (65%)
• Gaps: 20/365 - (5%)

  Fly     9 VDTNPAPDPQAPITRKGFLMSLNTGTPMPIPEQNLFGRCRPVSEFEKLNRVGEGSYGIVYRARDT 73
            |..:||..|          :.|....|..:|.  |.| ||.|.||:.|||:.||:||:||||:|.
Mouse   396 VPDSPALSP----------IELKQELPKYLPA--LQG-CRSVEEFQCLNRIEEGTYGVVYRAKDK 447

  Fly    74 RSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVVGKSLDSIFLVMDFCEQDL 138
            :::||||||:::|::||:|.||:.||||..:.:..|.|||.:||:|||.::|.|::||::.|.||
Mouse   448 KTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDL 512

  Fly   139 ASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKVSNLLMTDKGCIKVADFGLARMFS 203
            .|:::.|.|||...|||.:.:|:|..:|:||..:::|||||.||||::..|.:||.||||||.:.
Mouse   513 KSLMETMKQPFLPGEVKTLMIQLLSGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYG 577

  Fly   204 NPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILGELLLGKPLLPGNSEIAQLDMIIDL 268
            :|.|..||.:|||||||||||||.:.::||||||:.|||.||||..|||.||.|:|.|::.|...
Mouse   578 SPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKD 642

  Fly   269 LGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKF-HMIGQSGRNLLNILFIYNPKTRATAEECL 332
            ||.|||.||||:.|||||:..|.|:.|||||..:| .::...|.:|:|....|.|..|..||:.|
Mouse   643 LGTPSEKIWPGYNDLPAVKKMTFSEYPYNNLRKRFGALLSDQGFDLMNKFLTYYPGRRINAEDGL 707

  Fly   333 KSKYFVDPPQACDPGMMPTFP----QHRNNAAPAPAVQPP 368
            |.:||.:.|...||.|.||:|    |.|.....:|  :||
Mouse   708 KHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSP--RPP 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	160/308 (52%)
		S_TKc	53..337	CDD:214567	147/284 (52%)
Cdk11b	NP_031687.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..401		1/4 (25%)
		STKc_CDC2L1	421..712	CDD:173741	151/290 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	722..784		9/26 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0663
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	1	1.000	-	-		FOG0001516
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R970
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850