Protein Alignment Cdc2rk and CDK2

DIOPT Version :10

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: XP_011536034.1
• Gene: CDK2 / 1017
• HGNCID: 1771
• Length: 346
• Species: Homo sapiens
• Alignment Length: 345
• Identity: 125/345 - (36%)
• Similarity: 194/345 - (56%)
• Gaps: 64/345 - (18%)

  Fly    50 VSEFEKLNRVGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVR 114
            :..|:|:.::|||:||:||:||:..:.|:|||||:|:|.|.:|:|.:.:|||.:||:.:|.|||:
Human     1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVK 65

  Fly   115 LREVVVGKSLDSIFLVMDFCEQDL-----ASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMI 174
            |.:|:  .:.:.::||.:|..|||     ||.|..:..|.    :|....|:|:.|.:.||..::
Human    66 LLDVI--HTENKLYLVFEFLHQDLKKFMDASALTGIPLPL----IKSYLFQLLQGLAFCHSHRVL 124

  Fly   175 HRDLKVSNLLMTDKGCIKVADFGLARMFSNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAF 239
            |||||..|||:..:|.||:|||||||.|..|.:..|.::|||||||||:||||:.::||||:|:.
Human   125 HRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSL 189

  Fly   240 GCILGEL-LLG-----------------------------------------------KPLLPGN 256
            |||..|: |:|                                               :.|.||:
Human   190 GCIFAEMHLVGTQHHARCCGEHRRNGRQSLCPLCSYLEVAASQGWGMTAVSTPYPVTRRALFPGD 254

  Fly   257 SEIAQLDMIIDLLGAPSESIWPGFADLPAVQ-NF-TLSQQPYNNLTPKFHMIGQSGRNLLNILFI 319
            |||.||..|...||.|.|.:|||...:|..: :| ..::|.::.:.|.   :.:.||:||:.:..
Human   255 SEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPP---LDEDGRSLLSQMLH 316

  Fly   320 YNPKTRATAEECLKSKYFVD 339
            |:|..|.:|:..|...:|.|
Human   317 YDPNKRISAKAALAHPFFQD 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	125/345 (36%)
CDK2	XP_011536034.1	STKc_CDK2_3	3..334	CDD:270844	123/339 (36%)