Protein Alignment Cdc2rk and cdk12

DIOPT Version :9

• Sequence 1: NP_523674.1
• Gene: Cdc2rk / 36051
• FlyBaseID: FBgn0013435
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: XP_003200579.2
• Gene: cdk12 / 100149834
• ZFINID: ZDB-GENE-081104-294
• Length: 1293
• Species: Danio rerio
• Alignment Length: 404
• Identity: 136/404 - (33%)
• Similarity: 217/404 - (53%)
• Gaps: 60/404 - (14%)

  Fly    12 NPAPDPQAPITRKGFLMSLNTGTPMPIPE------------------QNLFGRCRPVSEFEKLNR 58
            :|:| ||:|         .....|:..|.                  |..:|: |.|.:|:.:..
Zfish   627 DPSP-PQSP---------ARVSPPLLQPSFKKRPKICSPRYGERKQTQTDWGK-RCVDKFDIIGI 680

  Fly    59 VGEGSYGIVYRARDTRSNEIVALKKVRMDQEKDGLPISGLREIMILKQCHHENIVRLREVVVGK- 122
            :|||:||.||:|:|..:.|:|||||||:|.||:|.||:.:|||.||:|.:|.::|.::|:|..|
Zfish   681 IGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLNHRSVVNMKEIVTDKQ 745

  Fly   123 -SLD------SIFLVMDFCEQDLASVLDNMSQPFTESEVKCITLQVLKALKYLHSRFMIHRDLKV 180
             :||      :.:||.::.:.||..:|::....|:...|:....|:::.|.|.|.:..:|||:|.
Zfish   746 DALDFKKDKGAFYLVFEYMDHDLMGLLESGLVSFSHEHVQSFMRQLMEGLDYCHKKNFLHRDIKC 810

  Fly   181 SNLLMTDKGCIKVADFGLARMF-SNPPKPMTPQMVTLWYRAPELLLGCRTHTTAVDMWAFGCILG 244
            ||:|:.:.|.||:|||||||:: |...:|.|.:::|||||.||||||...::.|:|:|:.|||||
Zfish   811 SNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYSPAIDVWSCGCILG 875

  Fly   245 ELLLGKPLLPGNSEIAQLDMIIDLLGAPSESIWPGFADLPAVQNFTLSQQPYNNLTPKFHMIGQS 309
            ||...||:...|.|:.||::|..|.|:|..:.||....||........:|....|..:|..:...
Zfish   876 ELFTKKPIFQANQELLQLELISRLCGSPCPAAWPDVIRLPYFNTMRPKKQYRRRLREEFSFLPTP 940

  Fly   310 GRNLLNILFIYNPKTRATAEECLKSKYFVDPPQACDPGMMPTFPQHRNNAAPAPAVQPPADIP-I 373
            ..:||:.:...:|..|.|||:.|.|::..|    .:|..|                 ||.|:| .
Zfish   941 ALDLLDHMLTLDPSRRCTAEQALASQFLCD----VEPNKM-----------------PPPDLPHW 984

  Fly   374 SDLLNVFIKRQRME 387
            .|...::.|::|.:
Zfish   985 QDCHELWSKKRRRQ 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc2rk	NP_523674.1	STKc_CDK10	45..353	CDD:173742	121/316 (38%)
		S_TKc	53..337	CDD:214567	115/292 (39%)
cdk12	XP_003200579.2	STKc_CDK12	667..968	CDD:270847	118/301 (39%)
		S_TKc	675..968	CDD:214567	115/292 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D925637at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920