Protein Alignment PIG-N and NPP2

DIOPT Version :10

• Sequence 1: NP_610549.1
• Gene: PIG-N / 36049
• FlyBaseID: FBgn0033479
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_010900.1
• Gene: NPP2 / 856699
• SGDID: S000000742
• Length: 493
• Species: Saccharomyces cerevisiae
• Alignment Length: 532
• Identity: 95/532 - (17%)
• Similarity: 178/532 - (33%)
• Gaps: 166/532 - (31%)

  Fly     3 IAYALVVHVLLLGSIFV---IYFR--SPVITG---LTPQKHLLYYGLEPPANRLVLIVTDGFRAD 59
            |:...::.:||.|.|.:   :|.:  .|:..|   :..:.:..:.|........:||..|||...
Yeast    25 ISRHFLLKLLLCGIILIELLLYSKCPKPIDNGPRTIANRSNTYFNGTHDFKTLTILISIDGFHPR 89

  Fly    60 SFFEENCRYVPNLRKIFLREGVVGVSRTRV-------PTETRPGHITLIAGLYEDPSAVLRGWKS 117
            ..   :.:|.|.|..:........::.|..       ||:|.|.|.:::.|.|
Yeast    90 LI---DAKYTPFLYNLHNLRSPYDMNITTAPYMIPSFPTQTFPNHWSMVTGKY------------ 139

  Fly   118 NPIDFDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDLD------------------- 163
             ||:...|.|     ..|.     |..|.......::.|.:::..|
Yeast   140 -PIEHGIVSN-----IFWD-----NFTSSEFRPNNLDARIWSNTADPIWQLLQTESQGEYKVATH 193

  Fly   164 FSPGYDAYEEDEWVFKRVKL-----------LLQQKREAL----------QRAQNVVFFLHLLGL 207
            ..||.:...||.....|.::           .||.|...:          .|.:.|:.::.  .:
Yeast   194 MWPGSEVVYEDHGDVPRERMPFYFGKFNQWEKLQDKLAQIFRYIDMPQLKDRPELVISYIP--NV 256

  Fly   208 DTAGHVHKPGAPKFRRTLEKTEKGVYAIYQEFERVFPD-----------KRTAYLLTADHGMTDS 261
            |:.||       .|...|.  :|.:..:..|.:..|.|           |.:..::.:||||  |
Yeast   257 DSYGH-------SFGYDLR--DKRLQKLIGEVDGFFLDLIEGLQKRNLLKISNVMIVSDHGM--S 310

  Fly   262 GAHGSGSPHETDTPFMLWGAGASRAVPKPGGRTFMPN--NEGPAMPL---HELEQAQLTPLMSAL 321
            ..:.:...|     .::|    .|..|......|:.:  ||||.|.:   :..::..:..|:.|.
Yeast   311 NVNANDGEH-----VVVW----ERVFPADAMSAFISHLYNEGPMMMVCLKNPRDKQWICDLIEAQ 366

  Fly   322 LGLAPPMNNFGKLPLGYLNVSKEYEAMAAHVNALQLLEQ-----YVALQKQHKKGFFADILLEYD 381
            |..|     :|.      .:|:::     ||    :|::     :...|..::|..:.|.:.:..
Yeast   367 LEKA-----YGD------EISRKF-----HV----ILKEDFDPSWKYFQYDNRKHRYDDRVGDIW 411

  Fly   382 VLNAE---AIKRYKDTIVQLQKKREYSL--CIDKSQVIMSQA----------LEGIDYYHGYYRR 431
            :|..|   .:|...|..:.:.....|:.  |.|.:.:.:...          .|.|:.|:
Yeast   412 ILADEYYAIVKEMGDVPIGIMGTHGYNFNNCSDMASIFIGMGPMFNNEVVPPFENIEVYN----- 471

  Fly   432 VLLLSTTSTFLG 443
              :|...|..||
Yeast   472 --MLIKASALLG 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-N	NP_610549.1	GPI_EPT_1	42..335	CDD:293744	65/355 (18%)
		PigN	420..834	CDD:461508	7/24 (29%)
NPP2	NP_010900.1	Enpp	78..481	CDD:293742	84/477 (18%)