Protein Alignment PIG-N and GPI13

DIOPT Version :9

• Sequence 1: NP_610549.1
• Gene: PIG-N / 36049
• FlyBaseID: FBgn0033479
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_013069.1
• Gene: GPI13 / 850628
• SGDID: S000003954
• Length: 1017
• Species: Saccharomyces cerevisiae
• Alignment Length: 1030
• Identity: 194/1030 - (18%)
• Similarity: 350/1030 - (33%)
• Gaps: 327/1030 - (31%)

  Fly     7 LVVHVLLLGSIFVIYFRSPVITGLTPQKHLL--------YYGLEPPANRLVLIVTDGFRAD---- 59
            |:|.:.:|..|.:.:|    ..|....:|:|        ...|.|..|:.|::|.|..|.|
Yeast    38 LLVFIAILQFISIAFF----TRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFAIP 98

  Fly    60 ---SFFEENCRYVPNLRKIF-----------------------LREGVVGVSRTRVPTETRPGHI 98
               |....|..|..|:..::                       ..:.:.|::...:||
Yeast    99 VNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPT------- 156

  Fly    99 TLIAGLYEDPSAVLRGWKSNPIDFDTVFNRSSQTYAWGANDVLNVFSH--VSNGG----EINLRF 157
                  :.|..:...|......:|....:.:::|..:..:|......|  :||..    .:|:
Yeast   157 ------FIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNV-- 213

  Fly   158 YNHDLD-FSPGYDAYEEDEWVFKRVKLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKF 221
              .||| ...|...|..|.         |||.:|.      .|...|:||:|..||.:.|.....
Yeast   214 --WDLDTVDNGVMDYFHDH---------LQQDKEW------DVMIGHMLGIDHVGHKYGPDHFTM 261

  Fly   222 RRTLEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGAHGSGSPHETDTPFMLWGAGASRA 286
            |....:.::.:..|.:..     |..|..::..||||..:|.||..|..|.::...|:.
Yeast   262 REKQIQVDQFIDWILKSI-----DDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYS------ 315

  Fly   287 VPKPG----GRTFMPNNEGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKEYEA 347
             .||.    ..|...|.:........:.|..|...::.|:|...|.||.| .|:.  .:::....
Yeast   316 -KKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLG-WPID--EIARNDRE 376

  Fly   348 MAAHVNA----LQLL------------------------------EQYVALQKQHKKGFF---AD 375
            .:..||:    |||.                              |::|.|..:::|.|.   .:
Yeast   377 WSQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKYQKVFLQTCEE 441

  Fly   376 ILLEYDVLN-AEAIKRYKDTIVQLQKKREYSLCIDK--SQVIMSQALEGIDYYHGYYRRVLLLST 437
            :..::|..: |..|.....::|.|       :.|.|  ..::::|.:.  ::..|..  :::|.|
Yeast   442 LWAKFDYYSIATGITLLATSLVLL-------ISITKLIPSIVVNQMVP--EFVPGII--IMVLVT 495

  Fly   438 TSTFLGWMFYIYRLLSRNRASKVELVLERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLLP 502
            ...|.| :||:|:     :.|.|:       :.....:.:::.::|.|.::          :...
Yeast   496 NLCFHG-IFYVYQ-----QPSFVD-------QFWGTLLATAIGIIIGCYIT----------IFDR 537

  Fly   503 Y-FVWLKALQPWNINFSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFAC 566
            | |:|:.      :....:.|..:|..|:...:...:|..:.:    ||.:|.|::|.....|..
Yeast   538 YNFIWIA------MRLGETLADYWSRIAVMFMIIHALLFTSNS----FTIWEDRIVAFLLSTFGM 592

  Fly   567 YNSWENFQWKSRDFFSWLALVLILSCFPLLPLSVGYQNG---------------------YLLG- 609
            ...:|           ::.|....|...||..::..:.|                     .|||
Yeast   593 LTLYE-----------FVFLPKRQSTTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGG 646

  Fly   610 --AGVIVIFTNSFWNSKSRLCYRNHTKYSNALILLQTILCAYLHSNGINIPIPLKLASWLYLVYA 672
              :.|::|||.  ..|...:|.....:|           |....:|..|       :||..|...
Yeast   647 YHSAVLIIFTR--LASMITICREEQGEY-----------CIPTFNNQNN-------SSWWVLGLC 691

  Fly   673 FASILLSKESRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNISLRAQSARAERSVLRLA 737
            |..|.:       |.....|      |..|.:||:|.    ..|.:|:.|        :.:|.|.
Yeast   692 FLMIFI-------LPACITG------YYNLTSSYQAA----APIWINVFL--------KGILGLN 731

  Fly   738 FTLLLYTFFSLFGSGNIASISSF----DPNIARCYLSHFAPFVIMGLVLLK-----LLVPVVLIM 793
            |     .::||....|.:::.:.    |..|.:..|:.    :|.|..|:.     |:.|:.:.:
Yeast   732 F-----VYWSLTSLENNSAVIAIPFLRDVTIFKFTLAR----IIAGFSLIASNVGWLMGPLCIKL 787

  Fly   794 SVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEVTTLVMLVI 858
            ::   ::..|:.||..|    |...::.|..|..||        |...||  :::....|..|..
Yeast   788 NI---HNTDVKSHEATI----LGYTNIYGSEFFLLV--------INVLIS--ILLFNKPLAQLSY 835

  Fly   859 FYTAKQLLRVIPWEEIDFKML------PLRL-------------------IHWDV 888
            |....|||.::  |.||...|      |:.|                   :.||:
Yeast   836 FLMCNQLLSIL--EIIDLLKLKENIIGPIALGLLSYQHFFTTGHQATIPSVQWDI 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-N	NP_610549.1	Npp1	10..>265	CDD:224441	57/299 (19%)
		GPI_EPT_1	42..335	CDD:293744	67/333 (20%)
		PigN	421..834	CDD:282796	82/446 (18%)
GPI13	NP_013069.1	Npp1	48..701	CDD:224441	142/785 (18%)
		GPI_EPT_3	77..367	CDD:293747	67/334 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810