DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PIG-N and NPP1

DIOPT Version :9

Sequence 1:	NP_610549.1	Gene:	PIG-N / 36049	FlyBaseID:	FBgn0033479	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_009955.2	Gene:	NPP1 / 850391	SGDID:	S000000621	Length:	742	Species:	Saccharomyces cerevisiae

Alignment Length:	259	Identity:	53/259 - (20%)
Similarity:	103/259 - (39%)	Gaps:	56/259 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 VLIVTDGFRADSFFEENCRYVPNLRKIFLREGVVGVSRT-----RVPTETRPGHITLIAGLYE-- 106
            ::|..|||......:.|..::.:|.:: ..:|.:.::.|     ..||||.|.|.||:.|.|.
Yeast   171 IVISLDGFHPSLISKRNTPFLHDLYEL-KYDGGMNITSTPFMVPSFPTETFPNHWTLVTGQYPIH 234

  Fly   107 ---------DPS-------AVL--RGWKSNPIDFDTVFNRSSQTY--AWGANDVLNVFSHVSNGG 151
                     ||.       .||  |.|.:|  |.:.::    ||.  |:..:......:|:..|.
Yeast   235 HGIVSNVFWDPDLNEEFHPGVLDPRIWNNN--DTEPIW----QTVQSAFDGDIPFKAATHMWPGS 293

  Fly   152 EINLRFYNHD-----------LDFSPGY-DAYEEDEWVFKRVKLLLQQKREALQRAQNVVFFLHL 204
            ::|...||.:           .:.:|.| |.:...|.:.:::..:::....:....:..:...::
Yeast   294 DVNYTKYNEEKLQPEHKNPIARERTPFYFDEFNAKEPLSQKLSKIIEYVDMSTLNERPQLILGYV 358

  Fly   205 LGLDTAGHVHKPGAPK--------FRRTLEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTD 260
            ..:|..||.|  |.|.        |..||.:.:..:..:.:..:.......|..::.:||||:|
Yeast   359 PNVDAFGHKH--GYPSESEYYYEDFTETLGEVDTFLKQLVESLQERNLTSFTNLVIVSDHGMSD 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-N	NP_610549.1	Npp1	10..>265	CDD:224441	53/259 (20%)
		GPI_EPT_1	42..335	CDD:293744	53/259 (20%)
		PigN	421..834	CDD:282796
NPP1	NP_009955.2	Phosphodiest	170..545	CDD:396300	53/259 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810