DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PIG-N and ENPP5

DIOPT Version :9

Sequence 1:	NP_610549.1	Gene:	PIG-N / 36049	FlyBaseID:	FBgn0033479	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_001277001.1	Gene:	ENPP5 / 59084	HGNCID:	13717	Length:	477	Species:	Homo sapiens

Alignment Length:	255	Identity:	57/255 - (22%)
Similarity:	98/255 - (38%)	Gaps:	67/255 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 YGLEPPANRLVLIVTDGFRADSFFEENCRYVPNLRKIFLREGVVGVSRTRV-PTETRPGHITLIA 102
            :.|:|...:::|:..||||.|..::..   .|:...| ::.||.....|.| .|:|.|.|.||:.
Human    21 FSLQPDQQKVLLVSFDGFRWDYLYKVP---TPHFHYI-MKYGVHVKQVTNVFITKTYPNHYTLVT 81

  Fly   103 GLYEDPSAVLRGWKSNPIDFDTVFNRSSQTYAWGANDVLNVF------------------SHVSN 149
            ||:.:...::    :|.: ||.:.|:|...      |.:|::                  .|.|.
Human    82 GLFAENHGIV----ANDM-FDPIRNKSFSL------DHMNIYDSKFWEEATPIWITNQRAGHTSG 135

  Fly   150 GG-------EINLRFYNHDLDFSPGYDAYEEDEWVFKRVKLLLQ--QKREALQRAQNVVFFLHLL 205
            ..       :|:.||..|       |..|.|......||..:::  ..:|.:.           |
Human   136 AAMWPGTDVKIHKRFPTH-------YMPYNESVSFEDRVAKIIEWFTSKEPIN-----------L 182

  Fly   206 GL------DTAGHVHKPGAPKFRRTLEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMT 259
            ||      |..||...|.:|.....:...:|.:..:.|..::.........::|:|||||
Human   183 GLLYWEDPDDMGHHLGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMT 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-N	NP_610549.1	Npp1	10..>265	CDD:224441	57/255 (22%)
		GPI_EPT_1	42..335	CDD:293744	56/252 (22%)
		PigN	421..834	CDD:282796
ENPP5	NP_001277001.1	Phosphodiest	30..342	CDD:307681	55/246 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810