Protein Alignment PIG-N and Pigo

DIOPT Version :10

• Sequence 1: NP_610549.1
• Gene: PIG-N / 36049
• FlyBaseID: FBgn0033479
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_064419.3
• Gene: Pigo / 56703
• MGIID: 1861452
• Length: 1093
• Species: Mus musculus
• Alignment Length: 988
• Identity: 211/988 - (21%)
• Similarity: 338/988 - (34%)
• Gaps: 299/988 - (30%)

  Fly    46 NRLVLIVTDGFRADSFFEENCRYVPNLRKI---FLREGVVGVSRTRVPTETRPGHITLIAGLYED 107
            :|:||::.|..|.| |.:....:||....:   ||  |.:| |..|: .|::|.|..|.....:.
Mouse    68 SRVVLVLIDALRFD-FAQPQRSHVPGEPPVSVPFL--GKLG-SLQRI-LESQPHHGRLYRSQVDP 127

  Fly   108 PSAVLRGWK-----SNPIDFDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDL--DFS 165
            |:..::..|     |.|...|...|.:|...   ..|  ||...:::.|. .:.|...|.  |..
Mouse   128 PTTTMQRLKALTTGSLPTFIDAGSNFASHAI---VED--NVIQQLNSAGR-RVVFMGDDTWRDLF 186

  Fly   166 PGYDAYEEDEWVFKRVKL---------LLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKF 221
            ||  |:.: .:.|....:         :|:.....|......|...|.||:|..||.|.|..|:.
Mouse   187 PG--AFSQ-AFFFSSFNVRDLHTVDNGILEHLYPTLDGGSWDVLIAHFLGVDHCGHKHGPHHPEM 248

  Fly   222 RRTLEKTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGAHGSGSPHETDTPFMLWGAGASRA 286
            .:.|.:.::.:..:.:..|     ..|..::..|||||.:|.||..|..|......|
Mouse   249 AKKLSQMDQVIQGLIERLE-----NDTLLVVAGDHGMTMNGDHGGDSELEVSAALFL-------- 300

  Fly   287 VPKPGGRTFMPNNEGPAMPLHELE---QAQLTPLMSALLGLAPPMNNFGKL---------PLGYL 339
                    :.|....|::|..|.|   |..|.|.::.||||..|..|.|::         ...:.
Mouse   301 --------YSPTALFPSVPPEEPEVIPQVSLVPTLALLLGLPIPFGNTGEVMAELFSGGSDSSHP 357

  Fly   340 NVSKEYEAMAAHVNALQL---LEQYVA------LQKQHK-KGFFADILLEY-----DVLNAEAIK 389
            :.|...:..|.|:||.|:   |..|.|      :::.|: :..|:.....|     |...|||..
Mouse   358 HSSALAQVSALHINAQQVSRFLHTYSAATQDLQVKELHRLQTLFSKASARYQHFLRDPQEAEAAL 422

  Fly   390 RYKDTIVQLQKKREYSLCIDK--------------------------SQVIMSQALEGIDYYHGY 428
            .......|...:...:|||:.                          ||:.::.         |:
Mouse   423 STLTAEFQQFLRGARALCIESWARFSLVRMAGGAALLAAACLLCLLASQLAVAP---------GF 478

  Fly   429 YRRVLLLSTTSTFLGWMFYIYRLLSRNRASKVELVLERSNKIVRVSIVSSVI------------- 480
            ..|.|||...:..|.|.. :|..:|....||::||:     :..|:...|::
Mouse   479 LFRPLLLIPVAWGLTWTI-LYAGVSVTTGSKIDLVV-----LGAVAAAGSLLPFLWKAWVSRGSK 537

  Fly   481 ------------VLIICLLSQGTPLDISF---------YLL--LPYFV-----WL-KALQPWNIN 516
                        |||:.|:...|....||         :||  |.:|:     |. :.|.|..:.
Mouse   538 RPLAPLLPVPRPVLILLLIRLATFFSDSFVVAEARATPFLLGSLVFFLVAQLHWEGQLLPPKPLT 602

  Fly   517 FSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCF-C---VFACYNSWENFQWKS 577
            .|...:||.:.|...:....|.|.|.   |::||    ||..|.. |   ..||.:|
Mouse   603 MSRLGSSAPTAPPRHSGAHALWLGIG---LLLFT----RLAGLFHRCPEETPACRSS-------- 652

  Fly   578 RDFFSWLALVLILSCFPLLPLSVGYQN----GYLLGAGVIVIFTNSFW-----NSKSRLCYRNHT 633
                .||:        ||..:..|...    |..:||.|.::.....|     |.||........
Mouse   653 ----PWLS--------PLASMVGGRAKNLWYGACVGALVALLVVVRLWLRRYGNLKSPEPPVLFV 705

  Fly   634 KYSNALILLQTILCAYLHSNGINIPIPLKLASWLYLVYAFASILLSKESRLDLRLAQIGFNLGSL 698
            ::...|::|.|.....|.|.....|..|:      .:.|.||.:|   .|..:.||.:|
Mouse   706 RWGMPLMVLGTAAYWALASGAEEAPPRLR------ALVAGASAVL---PRAVMGLAALG------ 755

  Fly   699 YATLCTSYEAVFVQLLTIELNISLRAQSARAERSVLRLAFTLLLYTFFSLFGSGNIASISSFD-- 761
                       .|.||...:.:.::|.:|.:....:...|            ||...|.:..|
Mouse   756 -----------LVLLLWRPVTVLVKAGAATSRTRTILTPF------------SGPPTSQADLDYV 797

  Fly   762 -PNIARCYLSHF----------APFVI------------MGLVLLKLLVPVVLIMSVIYANSEFV 803
             |.|.|.....|          .|..:            |...||.|..|::|:
Mouse   798 VPQIYRHMQEEFQGRLERTKAQGPITVAAYQLGSVYSAAMVTALLLLAFPLMLL----------- 851

  Fly   804 RQHEEQIFICLLLICDVMGLNFLFL--------VRNQGSWLDIGTSISHFVIMEVTTLVMLVIFY 860
              |.|::.:..||:   ...:||.|        |...|.:..:..::|.:|::...|      ||
Mouse   852 --HVERVSLVFLLL---FLQSFLLLHLLAAGTPVATPGPFTVLWQAVSAWVLLATQT------FY 905

  Fly   861 TA--KQLLRVIPW 871
            :.  :.:...|.|
Mouse   906 STGHQPVFSAIHW 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-N	NP_610549.1	GPI_EPT_1	42..335	CDD:293744	78/319 (24%)
		PigN	420..834	CDD:461508	103/501 (21%)
Pigo	NP_064419.3	GPI_EPT_3	64..344	CDD:293747	78/310 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	971..991