DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PIG-N and enpp7.2

DIOPT Version :9

Sequence 1:	NP_610549.1	Gene:	PIG-N / 36049	FlyBaseID:	FBgn0033479	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_001314969.1	Gene:	enpp7.2 / 557817	ZFINID:	ZDB-GENE-130531-2	Length:	484	Species:	Danio rerio

Alignment Length:	409	Identity:	102/409 - (24%)
Similarity:	148/409 - (36%)	Gaps:	131/409 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPA--------NRLVLIVTDGFRADSFFEENCR 67
            :||..||.::.|.:               .|..||        |:|:||..||||.|  ::.:..
Zfish     1 MLLALSILLLVFPA---------------SLSAPARDRCTRGRNKLLLISFDGFRWD--YDRDVD 48

  Fly    68 YVPNLRKIFLREGVVGVSRTRVP----TETRPGHITLIAGLYEDPSAVLRG-WKSNPIDFDTVFN 127
             .|||.|:    .|.||....|.    |.|.|.|.||::|.|.:...|:.. |      |:|...
Zfish    49 -TPNLDKM----AVDGVKAAYVTPPYLTITSPSHFTLLSGRYIENHGVIHNVW------FNTTTR 102

  Fly   128 RSSQTYA-------WGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKRVKLLL 185
            :..:.|.       |. |..|.::......|     .....|.| ||..|..::|.|
Zfish   103 QRKEYYMTQFVDDYWD-NGTLPIWITAQRQG-----LKTGSLHF-PGTAATYQNETV-------- 152

  Fly   186 QQKREALQRA-----------------------QNVVFF-LHLLGLDTAGHVHKPGAPKFRRTLE 226
             |:||...||                       |::.|. |:....|.:||.|.|.:|:.|..::
Zfish   153 -QEREVEPRAYDYTNETAWKENVDKVMKDWFKEQDLDFVTLYFGDPDESGHKHGPDSPERREAVK 216

  Fly   227 KTEKGVYAIYQEFERVFPDKRTAYLLTADHGMTDSGAHGSGSPHE---TDTP--------FMLWG 280
            |.::.|..|.:..|::........::||||||  |.........|   ||.|        |.|..
Zfish   217 KVDRTVGYIRETAEKLGLSDHMNIIITADHGM--STVFKGDQVKEIVLTDIPGFSYKDLQFHLLD 279

  Fly   281 AG-ASRAVPK-----------PGGRTFMPN------NEGPAMPLHELEQAQLTPLM------SAL 321
            .| .:..:||           .||.   ||      .:.||. ||..:..:|.|::      ..:
Zfish   280 YGPTAMLLPKEGLLDKVYNALKGGH---PNLHIYKKEDMPAR-LHYSKHPRLLPIILYADPGYVI 340

  Fly   322 LGLAPPMNNFGKLPLGYLN 340
            .|..|..||.|:  .||.|
Zfish   341 SGFYPLQNNKGE--HGYDN 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-N	NP_610549.1	Npp1	10..>265	CDD:224441	75/297 (25%)
		GPI_EPT_1	42..335	CDD:293744	93/371 (25%)
		PigN	421..834	CDD:282796
enpp7.2	NP_001314969.1	Enpp	29..396	CDD:293742	94/366 (26%)
enpp7.2	NP_001314969.1	Phosphodiest	31..356	CDD:279931	91/361 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810