Protein Alignment PIG-N and pign

DIOPT Version :10

• Sequence 1: NP_610549.1
• Gene: PIG-N / 36049
• FlyBaseID: FBgn0033479
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_001297009.1
• Gene: pign / 556797
• ZFINID: ZDB-GENE-080204-114
• Length: 932
• Species: Danio rerio
• Alignment Length: 934
• Identity: 329/934 - (35%)
• Similarity: 495/934 - (52%)
• Gaps: 96/934 - (10%)

  Fly     7 LVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSFF---EENCRY 68
            |:|||:....||.|||.||::.|:|||:    ..|.|||.||||.|.||.||||.|   :.....
Zfish    11 LIVHVVFFLCIFDIYFTSPLVHGMTPQR----VSLPPPAKRLVLFVADGLRADSLFKPDDSGTSR 71

  Fly    69 VPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPIDFDTVFNRSSQTY 133
            .|.||.:....|..|||.||||||:||||:.||||.|||.|||.:|||.||::||:|||.|..|:
Zfish    72 APYLRSVIEEGGTWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSVFNESRYTW 136

  Fly   134 AWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKRVKLLLQQKR------EAL 192
            .||:.|:|.:|:..:.|..:....|..:.:.....||...|.|||..||..|...:      :.|
Zfish   137 CWGSPDILPMFAKGATGDHVYTHTYPPEREDFASTDASRLDTWVFDEVKDFLTAAKSNETLLKKL 201

  Fly   193 QRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIYQEFERVF-PDKRTAYLLTADH 256
            ...|| ||||||||:||.||.|:|.:.:....:...:.||..|....:..: .|.:|||:.|:||
Zfish   202 HEEQN-VFFLHLLGIDTNGHAHRPMSKECLENIGLVDAGVADIVTVMDDFYGHDGKTAYVFTSDH 265

  Fly   257 GMTDSGAHGSGSPHETDTPFMLWGAGASRAVPKPGGRTFMPNNEGPAMPLH-----ELEQAQLTP 316
            |||:.|:||:|.|.||.||.::||||..:|..:...:  ..:|......|.     ::.||.:.|
Zfish   266 GMTNWGSHGAGHPSETLTPLVVWGAGVQKAQWETSQK--YEDNYLKEWGLESYRRVDVNQADIAP 328

  Fly   317 LMSALLGLAPPMNNFGKLPLGYLNVSKEYEAMAAHVNALQLLEQYVALQKQHKKGFFADILLEY- 380
            |||:|:|:..|:|:.|.|||.|||.|:.::|.:.:.||:|:|||:.....|.|:...:.:...|
Zfish   329 LMSSLIGIPFPLNSVGVLPLSYLNNSQHFKAESMYANAIQILEQFRVKLAQKKETTISFLFTPYQ 393

  Fly   381 ---DVLNAEAIKRYKDTIVQLQKKREYSLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFL 442
               |....:.|::.:|.|    :|..:...|...:.:::||:||:.|||.|.|..|..|....|:
Zfish   394 PLTDSKQVDFIRQARDLI----QKGRFDEAIVYCKDLIAQAMEGLSYYHTYDRLFLGSSVVLGFI 454

  Fly   443 GWMFYIYRLLSRNRAS------KVELVLERSNKIVRVSIVSSVIVLIICLLSQGTPLDISFYLLL 501
            ||..|:...:.:..||      ...:|.||   ::....:...:::.:.||.|.:|.....|.|:
Zfish   455 GWTSYVVLYILKTHASLRKPPTNTSMVTER---LLGWGFLCVGLLMALFLLVQSSPWSYYIYSLM 516

  Fly   502 PYFVWLKALQPWNINFSSSPASAYSVPALQ-TSMWQLVLLIACA-ELMVFTFFERRLIALCFCVF 564
            |..||...|:    .|.:......|:|:|. |..:...:|:|.. ||:|.:||.|.:::|...|.
Zfish   517 PVAVWYAVLK----EFKTLVGLVRSIPSLPLTKCFGYFVLVAFGIELLVMSFFYRAMLSLGLVVL 577

  Fly   565 ACYNSWENFQWKSR-DFFSWLALVLILSCFPLLPLSVGYQN--GYLLGAGVIVIFTNS--FWNS- 623
            |.:.....|..|:: ...||....|.|:.|||||: ||.:.  .|::.||.:::|.:|  .|:|
Zfish   578 ALWPVVSGFYTKAKFKSLSWTLSCLSLAVFPLLPV-VGREPNINYVISAGGLILFNSSSFLWSSW 641

  Fly   624 -KSRLCYRNHTKYSNALILLQTILCAY----LHSN---GINIPIPLKLASWLYLVYAFASILLSK 680
             .|.|..|:...:  ...::|..||||    .||:   ...:||..:|.||..||.:|...|||
Zfish   642 RDSPLMRRDRQLF--IFQMVQVALCAYTLTSTHSSLQLKQGLPIFNQLVSWSTLVSSFLIPLLS- 703

  Fly   681 ESRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLT--------IELN-ISLRAQSARAERSV--- 733
            .:||..||..|..:|..:|..|.|.:||:|..:|:        ||.. :|.:..|.|.|.|.
Zfish   704 STRLFHRLLSILMSLTCVYLLLSTGHEALFPLMLSWLMLAWIHIEQEAMSRQGSSNRNELSCIDF 768

  Fly   734 ----------------LRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVL 782
                            :|.::..:.:...:.||.||||||:||||....|:|:.|.||::.||::
Zfish   769 AENIDITKVRQLRLDDIRKSYFFVFFIIIAFFGCGNIASINSFDPASVYCFLTVFNPFIMGGLLM 833

  Fly   783 LKLLVPVVLIMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVI 847
            .|:|:|.|::|....:.....:.....:|:.:|:|.|:|.|:|.|||::.||||||||||||:||
Zfish   834 WKVLIPFVIVMCTFESIQVSTQLSSRSLFLIVLVISDLMALHFFFLVKDYGSWLDIGTSISHYVI 898

  Fly   848 -MEVTTLVMLVI----FYTAKQLL 866
             |.:|..:||:.    ..|:|::|
Zfish   899 VMSMTIFLMLLSVMTHILTSKKIL 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-N	NP_610549.1	GPI_EPT_1	42..335	CDD:293744	127/307 (41%)
		PigN	420..834	CDD:461508	140/463 (30%)
pign	NP_001297009.1	GPI_EPT_1	42..347	CDD:293744	127/307 (41%)
		PigN	432..885	CDD:461508	140/463 (30%)