DRSC/TRiP Functional Genomics Resources

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Protein Alignment magu and SPARCL1

DIOPT Version :9

Sequence 1:NP_610548.2 Gene:magu / 36048 FlyBaseID:FBgn0262169 Length:613 Species:Drosophila melanogaster
Sequence 2:NP_001121782.1 Gene:SPARCL1 / 8404 HGNCID:11220 Length:664 Species:Homo sapiens


Alignment Length:283 Identity:70/283 - (24%)
Similarity:101/283 - (35%) Gaps:100/283 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 KSDDQLMKLPACAAKQGECDDNEGP-----------VCGTDGQTYPTRCHLLRAQC------GGH 67
            |:|.|  ..|.|.     |.|   |           |||||.|||.:.|||...:|      .||
Human   445 KADQQ--GKPHCV-----CQD---PVTCPPTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGH 499

  Fly    68 QVSLKYSGSCNA---C--LEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGR 127
            |:.|.|.|:|.:   |  .|.::|..|.::......            ||.|..|    |:..|.
Human   500 QLQLDYFGACKSIPTCTDFEVIQFPLRMRDWLKNIL------------MQLYEAN----SEHAGY 548

  Fly   128 PIADDNKQFRRKGKLRCRANRRDRRRLA-SHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFN 191
            .    |::.|.|.|   :....::|.|| .|.|..                              
Human   549 L----NEKQRNKVK---KIYLDEKRLLAGDHPIDL------------------------------ 576

  Fly   192 TNLMRMFRNEAQSFFRQPSLSDSHILEWQFSKLDTNG-NKLLDRQEIRELKKVLRRNVKPRRCGR 255
              |:|.|:.....:.        :.:.||||:||.:. :::|...|:..|:..|   |....|..
Human   577 --LLRDFKKNYHMYV--------YPVHWQFSELDQHPMDRVLTHSELAPLRASL---VPMEHCIT 628

  Fly   256 TFGKYCDVTKDANLNWLEWSVCF 278
            .|.:.||..||.::...||..||
Human   629 RFFEECDPNKDKHITLKEWGHCF 651

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maguNP_610548.2 KAZAL_FS 38..77 CDD:238052 21/55 (38%)
TY 88..139 CDD:238114 9/50 (18%)
SPARC_Ca_bdg 180..274 CDD:287550 20/94 (21%)
SPARC_EC <219..281 CDD:238155 21/61 (34%)
TY 396..463 CDD:238114
SPARCL1NP_001121782.1 O-glycosylated at one additional site 25..34
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 28..360
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 388..426
KAZAL_FS 433..512 CDD:294071 27/76 (36%)
SPARC_Ca_bdg 513..648 CDD:287550 40/200 (20%)
SPARC_EC 514..662 CDD:238155 43/204 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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