DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and igfbp2b

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001119936.1	Gene:	igfbp2b / 798920	ZFINID:	ZDB-GENE-090107-3	Length:	265	Species:	Danio rerio

Alignment Length:	168	Identity:	39/168 - (23%)
Similarity:	53/168 - (31%)	Gaps:	50/168 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   317 HRGHTNTIGTGVNP-------HSYSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIP 374
            |.|..|  ||...|       :.|.::.:.::.|.                       :.||.
Zfish   114 HSGEVN--GTRSPPMKKPGKDYQYIKEIAVNKHHN-----------------------NKRTR-- 151

  Fly   375 SLYMLNSKPETASQDLENDSNCWMDQSVTLEEQG----HGGKSV------LFVPQCLPDGRYQRI 429
             :|.....|:|..   ...|.|..:....||...    |..|..      |..|.|...|:|...
Zfish   152 -MYNTQDDPKTPH---PKQSQCQQELDKVLENISRMAFHDNKGPLENLYDLKFPNCDKTGQYNLK 212

  Fly   430 QCYSST--STSYCWCVNEDTGKSIPGTSVKNKRPQCDE 465
            ||:.||  ....|||||..||..||.:......|.|.:
Zfish   213 QCHMSTHGQRGECWCVNPYTGVQIPSSDKVRGDPNCSQ 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052
		TY	88..139	CDD:238114
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114	24/78 (31%)
igfbp2b	NP_001119936.1	IB	21..97	CDD:197525
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	107..128		6/15 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	144..170		7/54 (13%)
		Thyroglobulin_1	169..248	CDD:278514	24/78 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	238..265		2/13 (15%)
		Cell attachment site. /evidence=ECO:0000255	243..245		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000