DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and igfbp5a

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001092224.1	Gene:	igfbp5a / 795084	ZFINID:	ZDB-GENE-070620-8	Length:	268	Species:	Danio rerio

Alignment Length:	189	Identity:	44/189 - (23%)
Similarity:	58/189 - (30%)	Gaps:	61/189 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 HTNTIGTGV------NPHSYSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLP-SSRTHIPSLY 377
            |....|.||      :|:.........|..||......|     ||....|.:| ..|.||
Zfish    89 HALLYGKGVCMNEKLSPYKSMHMPKDQESDEDGMVSEVT-----EDLLPQAKVPLFQRDHI---- 144

  Fly   378 MLNSKPETASQDLENDSNCWMDQSVTLEEQGHGGKSV---------------------------- 414
              |||   .:|.:..|..   .|...|..:.|...|:
Zfish   145 --NSK---KAQAMRKDRK---RQQAKLRTRSHVDYSLFGMEKHQSDIGPCRRKLDGIVQRMKDTS 201

  Fly   415 ------LFVPQCLPDGRYQRIQCYSS--TSTSYCWCVNEDTGKSIPGTSVKNKRPQCDE 465
                  |::|.|...|.::|.||..|  .....||||::. |..:|||.......||.|
Zfish   202 RVMALSLYLPNCDKKGFFKRKQCKPSRGRKRGICWCVDKH-GVQMPGTDFNGGNIQCKE 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052
		TY	88..139	CDD:238114
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114	20/102 (20%)
igfbp5a	NP_001092224.1	IB	23..99	CDD:197525	4/9 (44%)
igfbp5a	NP_001092224.1	Thyroglobulin_1	186..257	CDD:278514	16/71 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000