DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment magu and SPARC

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001296373.1	Gene:	SPARC / 6678	HGNCID:	11219	Length:	341	Species:	Homo sapiens

Alignment Length:	261	Identity:	56/261 - (21%)
Similarity:	87/261 - (33%)	Gaps:	82/261 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQC------GGHQVSLKYSGSCN---ACL--EA 83
            :|.|..||.:    .||..|.:|:.:.||....:|      .||::.|.|.|.|.   .||  |.
Human   100 SCPAPIGEFE----KVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCLDSEL 160

  Fly    84 VKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADDNKQFRRKGKLRCRANR 148
            .:|..|.::......|....:|                         :||.....|.|||.:...
Human   161 TEFPLRMRDWLKNVLVTLYERD-------------------------EDNNLLTEKQKLRVKKIH 200

  Fly   149 RDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSD 213
            .:.:||                  |||.......::.....:|   |.:|.
Human   201 ENEKRL------------------EAGDHPVELLARDFEKNYN---MYIFP-------------- 230

  Fly   214 SHILEWQFSKLDTNG-NKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVC 277
               :.|||.:||.:. :..|...|:..|:..|   :....|...|.:.||:..|..:...||:.|
Human   231 ---VHWQFGQLDQHPIDGYLSHTELAPLRAPL---IPMEHCTTRFFETCDLDNDKYIALDEWAGC 289

  Fly   278 F 278
            |
Human   290 F 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	12/44 (27%)
		TY	88..139	CDD:238114	5/50 (10%)
		SPARC_Ca_bdg	180..274	CDD:287550	17/94 (18%)
		SPARC_EC	<219..281	CDD:238155	18/61 (30%)
		TY	396..463	CDD:238114
SPARC	NP_001296373.1	FSL_SPARC	71..152	CDD:238649	17/55 (31%)
		SPARC_Ca_bdg	153..287	CDD:287550	36/199 (18%)
		SPARC_EC	154..290	CDD:238155	37/201 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910