Protein Alignment magu and SMOC2

DIOPT Version :9

• Sequence 1: NP_610548.2
• Gene: magu / 36048
• FlyBaseID: FBgn0262169
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_011534367.1
• Gene: SMOC2 / 64094
• HGNCID: 20323
• Length: 475
• Species: Homo sapiens
• Alignment Length: 626
• Identity: 141/626 - (22%)
• Similarity: 213/626 - (34%)
• Gaps: 232/626 - (37%)

  Fly    15 FIATGKSDDQLMKLPACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQCGGHQVSLKYSGSC-- 77
            |:...:..|:...|....:.|       .|:|.:||:|:.:||...||:|...|:.:.|.|:|
Human    29 FLRVDQDKDKDCSLDCAGSPQ-------KPLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKD 86

  Fly    78 -NACLEAVKFARRQQERD-PGYFVPRCRKDGNFAAMQCYGNNG-CWCSDSQGRPIADDNKQFRRK 139
             :.|:...|:.:.|..:: ...|:|.|..||.::.:||:...| |||....||||:
Human    87 VSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPIS--------- 142

  Fly   140 GKLRCRANRRDRRRLASHQIGYNPDTSASKGSSEAGSTAHRT--CSKSDRSQFNTNLMRMFRNEA 202
                                              ..:.||:|  |..|    .|..|
Human   143 ----------------------------------GTAVAHKTPRCPGS----VNEKL-------- 161

  Fly   203 QSFFRQPSLSDSHILEWQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDA 267
                                                           |:|.|.  ||...:
Human   162 -----------------------------------------------PQREGT--GKTVSL---- 173

  Fly   268 NLNWLEWSVCFTKEFHNRSAVVNLLASSAATAPPHSTHYSIHNTNVNGHHRGHTNTIGTGVNPHS 332
                               .:.::|.|..|.||...|
Human   174 -------------------QIFSVLNSDDAAAPALET---------------------------- 191

  Fly   333 YSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIPSLYMLNSKPETASQDLENDSNCW 397
               ...|.|      ||.|:.|                   |:|:....|......:..:.|:|.
Human   192 ---QPQGDE------EDIASRY-------------------PTLWTEQVKSRQNKTNKNSVSSCD 228

  Fly   398 MDQSVTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKRPQ 462
            .:....|||........:.:|:|...|.|:.:||:  .||.|||||..|||:.|||||.:.::|:
Human   229 QEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCH--PSTGYCWCVLVDTGRPIPGTSTRYEQPK 291

  Fly   463 CDESVAVRPMK-----------GCTEPRKTQFLKELKAYLNTSLL-----PSSTTG--SNSSMWK 509
            ||.:....|.|           ||...:|.:||..:...|:|.::     |||::|  |......
Human   292 CDNTARAHPAKARDLYKGRQLQGCPGAKKHEFLTSVLDALSTDMVHAASDPSSSSGRLSEPDPSH 356

  Fly   510 TDDERIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLAEWL 574
            |.:||:....|..||||.:....::|.|.|:..:...|..::|.||...|||||.||.||:.|.:
Human   357 TLEERVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELM 421

  Fly   575 NCL-------------QATPRESATTAKPAQSNETAS--PK 600
            .||             :.|||..|.:....|.....|  ||
Human   422 GCLGVAKEDGKADTKKRHTPRGHAESTSNRQDAMVVSSRPK 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	13/38 (34%)
		TY	88..139	CDD:238114	16/52 (31%)
		SPARC_Ca_bdg	180..274	CDD:287550	10/95 (11%)
		SPARC_EC	<219..281	CDD:238155	5/61 (8%)
		TY	396..463	CDD:238114	26/66 (39%)
SMOC2	XP_011534367.1	KAZAL	39..84	CDD:197624	15/51 (29%)
		TY	90..153	CDD:238114	21/105 (20%)
		Thyroglob_assoc	154..223	CDD:293205	23/208 (11%)
		TY	226..292	CDD:238114	26/67 (39%)
		SPARC_EC	<363..424	CDD:238155	22/60 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158074
Domainoid	1	1.000	59	1.000	Domainoid score	I10670
eggNOG	1	0.900	-	-		E1_KOG4578
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I3765
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1057719at2759
OrthoFinder	1	1.000	-	-		FOG0004129
OrthoInspector	1	1.000	-	-		otm42301
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12352
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3895
SonicParanoid	1	1.000	-	-		X2872
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.890