Protein Alignment magu and Smoc1

DIOPT Version :9

• Sequence 1: NP_610548.2
• Gene: magu / 36048
• FlyBaseID: FBgn0262169
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001139689.1
• Gene: Smoc1 / 64075
• MGIID: 1929878
• Length: 463
• Species: Mus musculus
• Alignment Length: 614
• Identity: 132/614 - (21%)
• Similarity: 206/614 - (33%)
• Gaps: 236/614 - (38%)

  Fly    29 PACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQCGGHQVSLKYSGSC-----NAC----LEAV 84
            |.|...|.:      |:|.:||::|.:.|...||:|....:::.:.|.|     :.|    .:|:
Mouse    44 PHCPRTQPK------PICASDGRSYESMCEYQRAKCRDPALAVVHRGRCKDAGQSKCRLERAQAL 102

  Fly    85 KFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNG-CWCSDSQGRPIADDNKQFRRKGKLRCRANR 148
            :.|::.||   ..|||.|.:||:|..:||:...| |||....|:||:..:.|
Mouse   103 EQAKKPQE---AVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQ------------- 151

  Fly   149 RDRRRLASHQIGYNPDTSASKGSS--EAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFF----- 206
             ::..:.|   |...|...|:|:|  :.......|.:..|.|:....:      |.|..|
Mouse   152 -NKTPVCS---GPVTDKPLSQGNSGRKVSFRFFLTLNSDDGSKPTPTM------ETQPVFDGDEI 206

  Fly   207 RQPSLSDSHILEWQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNW 271
            ..|:|...|:                                              |.||:.||
Mouse   207 TAPTLWIKHL----------------------------------------------VIKDSKLN- 224

  Fly   272 LEWSVCFTKEFHNRSAVVNLLASSAATAPPHSTHYSIHNTNVNGHHRGHTNTIGTGVNPHSYSED 336
                                                  ||||....:.|
Mouse   225 --------------------------------------NTNVRNSEKVH---------------- 235

  Fly   337 ASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIPSLYMLNSKPETASQDLENDSNCWMDQS 401
                                                                      :|..::.
Mouse   236 ----------------------------------------------------------SCDQERQ 242

  Fly   402 VTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKRPQC--- 463
            ..|||.....:..:.:|:|.|.|.|:.:||:.  ||.|||||..|||:.:||||.:...|.|
Mouse   243 SALEEARQNPREGIVIPECAPGGLYKPVQCHQ--STGYCWCVLVDTGRPLPGTSTRYVMPSCESD 305

  Fly   464 --------DESVAVRPMKGCTEPRKTQFLKELKAYLNTSLL----PSSTTG----SNSSMWKTDD 512
                    |:....|.:.||.|.:|.:|:..|...|.|.::    .::.||    |......|.:
Mouse   306 ARAKSIEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLE 370

  Fly   513 ERIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLAEWLNCL 577
            ||:|...|..||.|.:...::||.|.|:..|...:..::|.::...|||:|.||.|||.|...||
Mouse   371 ERVAHWYFSQLDSNSSDDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCL 435

  Fly   578 QATPRESATTAKPAQSNETASPKFQGVNP 606
            ..:....:..:.|       ..|..|.||
Mouse   436 GVSKEGGSLGSFP-------QGKRAGTNP 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	10/38 (26%)
		TY	88..139	CDD:238114	19/51 (37%)
		SPARC_Ca_bdg	180..274	CDD:287550	14/98 (14%)
		SPARC_EC	<219..281	CDD:238155	5/61 (8%)
		TY	396..463	CDD:238114	26/66 (39%)
Smoc1	NP_001139689.1	KAZAL	42..86	CDD:197624	13/47 (28%)
		Thyroglobulin_1	94..157	CDD:278514	22/79 (28%)
		Thyroglob_assoc	158..227	CDD:293205	21/162 (13%)
		TY	236..302	CDD:238114	26/67 (39%)
		SPARC_EC	<374..435	CDD:238155	21/60 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848460
Domainoid	1	1.000	59	1.000	Domainoid score	I10614
eggNOG	1	0.900	-	-		E1_KOG4578
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3783
Isobase	1	0.950	-	0	Normalized mean entropy	S7093
OMA	1	1.010	-	-		QHG47194
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004129
OrthoInspector	1	1.000	-	-		otm44353
orthoMCL	1	0.900	-	-		OOG6_109000
Panther	1	1.100	-	-	LDO	PTHR12352
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3895
SonicParanoid	1	1.000	-	-		X2872
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.740