DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and tmeff1a

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_698980.5	Gene:	tmeff1a / 570409	ZFINID:	ZDB-GENE-070912-294	Length:	336	Species:	Danio rerio

Alignment Length:	237	Identity:	55/237 - (23%)
Similarity:	80/237 - (33%)	Gaps:	75/237 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 QGECDDNEGPVCGTDGQTYPTRCHLLRAQC----------GGH---------QVSLKYSGSCNAC 80
            |.:|.....||||:||.||.:.|.|.:|.|          .||         ...|:.||
Zfish    82 QFQCPRMFDPVCGSDGDTYHSECFLRQAACEQQSPITIITEGHCPDAESASGDTDLESSG----- 141

  Fly    81 LEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWC---SDSQG---RPI-ADDNKQFRR 138
            ||...::|....|    |...|.:|          :.|.||   .|..|   .|: ..|.:.:..
Zfish   142 LEPSSYSRCSSCR----FGAECDED----------SEGIWCVCNIDCGGYNLNPVCGSDGQSYSN 192

  Fly   139 KGKLRCRANRRDRRRLASHQIGYNPDTSASKGSSEAG-----------STAHRTCS-KSDRSQFN 191
            ..::| .|:...:.::....:|....::...|.:..|           |..|.||. |:|.:...
Zfish   193 PCQVR-EASCLKQAQINVRHLGQCSGSAVLVGGANVGRAMPCPEINSSSCVHGTCEMKNDLATCR 256

  Fly   192 TNLMRMFRNEAQSFFRQPSLSDSHILEWQFSKLDT--NGNKL 231
            .||               ..|..|.....||:|..  ||.||
Zfish   257 CNL---------------GFSGKHCELRDFSELYVVPNGQKL 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	18/57 (32%)
		TY	88..139	CDD:238114	12/57 (21%)
		SPARC_Ca_bdg	180..274	CDD:287550	15/55 (27%)
		SPARC_EC	<219..281	CDD:238155	7/15 (47%)
		TY	396..463	CDD:238114
tmeff1a	XP_698980.5	KAZAL	81..125	CDD:197624	15/42 (36%)
tmeff1a	XP_698980.5	KAZAL	169..215	CDD:197624	7/46 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910