DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and sparcl1

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001124077.1	Gene:	sparcl1 / 567331	ZFINID:	ZDB-GENE-060130-6	Length:	606	Species:	Danio rerio

Alignment Length:	277	Identity:	66/277 - (23%)
Similarity:	105/277 - (37%)	Gaps:	83/277 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TGKSDDQLMKLPACAAKQ-GECDDNEGP---VCGTDGQTYPTRCHLLRAQCG------GHQVSLK 72
            |.|.:|:  ..|.|..:: .||..|...   |||||.:||.:.|||...:||      ||::.|.
Zfish   384 TCKLNDE--NKPLCVCQEPTECPPNVNDFEHVCGTDNKTYDSSCHLFATKCGLEGTKLGHRLHLD 446

  Fly    73 YSGSCN---ACLEA--VKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADD 132
            |:|||.   .|:|:  |:|..|.::         ..|:   ..:|.|.::    |.|.|...|
Zfish   447 YTGSCKFIAPCVESELVQFPLRMRD---------WLKN---VLLQLYEHD----SMSPGFLTA-- 493

  Fly   133 NKQFRRKGKLRCRANRRDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRM 197
                  |.::|.:......|||                  .||........:.....:|..:
Zfish   494 ------KQRIRVQKIYESERRL------------------HAGDHPVEILQQDFEKNYNMYI--- 531

  Fly   198 FRNEAQSFFRQPSLSDSHILEWQFSKLDTN-GNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYC 261
                             :.:.|||:::|.: .::.|...|:..|:..|   |....|...|.:.|
Zfish   532 -----------------YPVHWQFAQMDQHPSDRFLTHSELAPLRVPL---VPMEHCTSVFFQMC 576

  Fly   262 DVTKDANLNWLEWSVCF 278
            |..||..:::.||..||
Zfish   577 DADKDKLVSFKEWCSCF 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	19/47 (40%)
		TY	88..139	CDD:238114	8/50 (16%)
		SPARC_Ca_bdg	180..274	CDD:287550	16/94 (17%)
		SPARC_EC	<219..281	CDD:238155	19/61 (31%)
		TY	396..463	CDD:238114
sparcl1	NP_001124077.1	MDN1	<38..332	CDD:331582
		KAZAL_FS	373..454	CDD:320757	27/71 (38%)
		EFh_SPARC_EC	457..597	CDD:330171	39/202 (19%)
		EF-hand motif	530..562	CDD:320009	7/51 (14%)
		EF-hand motif	565..595	CDD:320009	10/29 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910