DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and Tmeff2

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_062764.1	Gene:	Tmeff2 / 56363	MGIID:	1861735	Length:	374	Species:	Mus musculus

Alignment Length:	231	Identity:	43/231 - (18%)
Similarity:	81/231 - (35%)	Gaps:	72/231 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TGKSDDQLMKL---PACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQC--------------- 64
            |.|.|.:.:::   ..|.. |.:|:.:..||||::|::|...|:|.:|.|
Mouse    73 TCKFDGECLRIGDTVTCVC-QFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCA 136

  Fly    65 -------------GGHQVSLKYSGSCNACLEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGN 116
                         |..:.|.|.:.:|:.|                .|...|.:|.......|
Mouse   137 TDTGSGSGDGVHEGSGETSQKETSTCDIC----------------QFGAECDEDAEDVWCVC--- 182

  Fly   117 NGCWCSDSQGRPI-ADDNKQFRRKGKLRCRANRRDRRRLASHQIGYNPDTSASKGSSEAGSTAHR 180
             ...||.:...|: |.|.|.:....::: .|:.:.:.::....:|...|.:.:...||.|..|
Mouse   183 -NIDCSQTNFNPLCASDGKSYDNACQIK-EASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYA-- 243

  Fly   181 TCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSDSHI 216
                  |:.:..|..::          :.|..:.||
Mouse   244 ------RTDYAENANKL----------EESAREHHI 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	14/66 (21%)
		TY	88..139	CDD:238114	10/51 (20%)
		SPARC_Ca_bdg	180..274	CDD:287550	5/37 (14%)
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114
Tmeff2	NP_062764.1	KAZAL_FS	95..135	CDD:238052	11/39 (28%)
		KAZAL	181..227	CDD:197624	9/50 (18%)
		PHA02887	<236..301	CDD:165214	9/46 (20%)
		Required for shedding. /evidence=ECO:0000250	303..320
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	353..374
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910