DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and sparc

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_989347.1	Gene:	sparc / 394973	XenbaseID:	XB-GENE-1009630	Length:	300	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	55/246 - (22%)
Similarity:	81/246 - (32%)	Gaps:	78/246 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VCGTDGQTYPTRCHLLRAQC------GGHQVSLKYSGSCN---ACL--EAVKFARRQQERDPGYF 98
            |||||.:||.:.||....:|      .||::.|.|.|.|.   .||  |..:|..|.::......
Frog   108 VCGTDNKTYESSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDNELSEFPLRMRDWLKNVL 172

  Fly    99 VPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADDNKQFRRKGKLRCRANRRDRRRLASHQIGYNP 163
            |....:|.|                         |.....|.|||.:....:.:||
Frog   173 VSLYERDEN-------------------------NNLLNEKQKLRVKKIHENEKRL--------- 203

  Fly   164 DTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSDSHILEWQFSKLDTNG 228
                     |||..:....::.....:|   |.:|.                 :.|||.:||.:.
Frog   204 ---------EAGDHSMELLARDFEKNYN---MYIFP-----------------VHWQFGQLDQHP 239

  Fly   229 -NKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVCF 278
             :..|...|:..|:..|   :....|...|...||...|..:...||:.||
Frog   240 IDGYLSHTELSPLRAPL---IPMEHCTTRFFDECDTDNDKYIALEEWAKCF 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	15/37 (41%)
		TY	88..139	CDD:238114	5/50 (10%)
		SPARC_Ca_bdg	180..274	CDD:287550	17/94 (18%)
		SPARC_EC	<219..281	CDD:238155	18/61 (30%)
		TY	396..463	CDD:238114
sparc	NP_989347.1	FSL_SPARC	68..149	CDD:238649	16/40 (40%)
		EFh_SPARC_SPARC	152..291	CDD:320014	39/202 (19%)
		EF-hand motif	224..257	CDD:320014	10/52 (19%)
		EF-hand motif	259..291	CDD:320014	9/29 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910