DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and IGFBP4

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001543.2	Gene:	IGFBP4 / 3487	HGNCID:	5473	Length:	258	Species:	Homo sapiens

Alignment Length:	98	Identity:	25/98 - (25%)
Similarity:	38/98 - (38%)	Gaps:	30/98 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 GSCNA----CLEAVKFARRQQERD----PGYFVPRCRKDGNFAAMQCY----GNNG-CWCSDSQG 126
            |||.:    .||.:..::.:...|    |   :|.|.::|||...||:    |..| |||.|
Human   172 GSCQSELHRALERLAASQSRTHEDLYIIP---IPNCDRNGNFHPKQCHPALDGQRGKCWCVD--- 230

  Fly   127 RPIADDNKQFRRKGKLRCRANRRDRRRLASHQI 159
                       ||..::.......:..|..||:
Human   231 -----------RKTGVKLPGGLEPKGELDCHQL 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	1/1 (100%)
		TY	88..139	CDD:238114	15/59 (25%)
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114
IGFBP4	NP_001543.2	IB	25..101	CDD:197525
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	149..172		25/98 (26%)
		Thyroglobulin_1	174..249	CDD:395039	21/91 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000