DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and igfbp1a

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_775390.3	Gene:	igfbp1a / 317638	ZFINID:	ZDB-GENE-021231-1	Length:	262	Species:	Danio rerio

Alignment Length:	163	Identity:	44/163 - (26%)
Similarity:	64/163 - (39%)	Gaps:	18/163 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 HTNTIGTGV---NP---HSYSEDASGSEEHEDNYE-DSATGYGGEEDDSQGADLPSSRTHIPSLY 377
            |..|.|..|   :|   ||.||.|   .:|.:::. .:|...|.......|...|.....|.:..
Zfish   101 HALTRGQAVCTESPEPNHSQSETA---PDHPESHNGPTAVNEGSSTVFVTGHGKPFDPRIITNKE 162

  Fly   378 MLNSKPETASQDLENDSNCWMD-----QSVTLEEQGHGGKSVLF-VPQCLPDGRYQRIQCYSST- 435
            .:.:|.....:.|.....|.::     ..:|..:|..|.|...| :|.|...|.|:..||.||.
Zfish   163 SMKAKVNAIRKKLVEQGPCHIELQTALDKITKSQQKLGDKLTRFYLPNCDKHGLYKIKQCESSLD 227

  Fly   436 -STSYCWCVNEDTGKSIPGTSVKNKRPQCDESV 467
             ....||||:...||.|||:|......:|.|.:
Zfish   228 GQRGKCWCVSSWNGKKIPGSSDLPADAECPEEL 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052
		TY	88..139	CDD:238114
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114	24/74 (32%)
igfbp1a	NP_775390.3	IB	34..111	CDD:197525	4/9 (44%)
igfbp1a	NP_775390.3	Thyroglobulin_1	181..256	CDD:306570	24/74 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000