DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment magu and Spock1

DIOPT Version :9

Sequence 1:NP_610548.2 Gene:magu / 36048 FlyBaseID:FBgn0262169 Length:613 Species:Drosophila melanogaster
Sequence 2:XP_038951544.1 Gene:Spock1 / 306759 RGDID:1311496 Length:444 Species:Rattus norvegicus


Alignment Length:495 Identity:103/495 - (20%)
Similarity:138/495 - (27%) Gaps:235/495 - (47%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 LMKLPACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQCG-GHQVSLKYSGSCNACLEAVKFAR 88
            |:|...|...|      ...|||:||.||.::|.|....|. |..:|....|.| .||       
  Rat   136 LVKCKPCPVAQ------SAMVCGSDGHTYTSKCKLEFHACSTGKSLSSLCDGPC-PCL------- 186

  Fly    89 RQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADDNKQFRRKGKLRCRANRRDRRR 153
              .|.:|....|:..|..              |:|.:.|.:|...|.:  .|.|...|||     
  Rat   187 --PEPEPEPQKPKAEKSA--------------CTDKELRNLASRLKDW--FGALHEDANR----- 228

  Fly   154 LASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSDSHILE 218
                                   ....|.|.:.:.:|:|:::             |...||  |.
  Rat   229 -----------------------VIKPTSSDTTQGRFDTSIL-------------PICKDS--LG 255

  Fly   219 WQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVCFTKEFH 283
            |.|:|||.|.:.|||..||   ..:.....:|  |.:.....||..||..|:..||..||.|.  
  Rat   256 WMFNKLDMNYDLLLDHSEI---NAIYLDKYEP--CIKPLFNSCDSFKDGKLSNNEWCYCFQKP-- 313

  Fly   284 NRSAVVNLLASSAATAPPHSTHYSIHNTNVNGHHRGHTNTIGTGVNPHSYSEDASGSEEHEDNYE 348
                                                                             
  Rat   314 ----------------------------------------------------------------- 313

  Fly   349 DSATGYGGEEDDSQGADLPSSRTHIPSLYMLNSKPETASQDLENDSNCWMDQSVTLEEQGHGGKS 413
                  ||         ||                      .:|:.|.....|        .|||
  Rat   314 ------GG---------LP----------------------CQNEMNRIQKLS--------KGKS 333

  Fly   414 VL--FVPQCLPDGRYQRIQCYSSTSTSYCWCV----NEDTGKSIPGTSVKNKRPQCDESVAVRPM 472
            :|  |:|:|..:|.|:..||:.  ||..||||    ||..|....||                  
  Rat   334 LLGAFIPRCNEEGYYKATQCHG--STGQCWCVDKYGNELAGSRKQGT------------------ 378

  Fly   473 KGCTEPRKTQFLKELKAYLNTSLLPSSTTGSNSSMWKTDD 512
            ..|.|.::|                |...||..|:...||
  Rat   379 VSCEEEQET----------------SGDFGSGGSVVLLDD 402

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maguNP_610548.2 KAZAL_FS 38..77 CDD:238052 13/39 (33%)
TY 88..139 CDD:238114 9/50 (18%)
SPARC_Ca_bdg 180..274 CDD:287550 26/93 (28%)
SPARC_EC <219..281 CDD:238155 22/61 (36%)
TY 396..463 CDD:238114 23/72 (32%)
Spock1XP_038951544.1 Kazal_2 139..>176 CDD:400135 13/42 (31%)
EFh_SPARC_EC 203..314 CDD:330171 41/233 (18%)
EF-hand motif 250..281 CDD:320009 14/35 (40%)
EF-hand motif 282..314 CDD:320009 12/106 (11%)
TY 317..378 CDD:238114 24/92 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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