DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and Igfbp6

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_037236.1	Gene:	Igfbp6 / 25641	RGDID:	2877	Length:	226	Species:	Rattus norvegicus

Alignment Length:	229	Identity:	47/229 - (20%)
Similarity:	69/229 - (30%)	Gaps:	98/229 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VTW-----------LAVFIATGKSDDQLMKLPAC---------------AAKQGECDDNEGPVCG 47
            :||           |.:..|.| |:..|...|.|               .|:.|.|...||..||
  Rat     1 MTWDGLPTQPLLMLLMLLFAAG-SESALAGCPGCGPGVQEEDAGSPADGCAETGGCFRREGQPCG 64

  Fly    48 T--------------DGQTYPTRCHLL-RAQC----GGHQVSLKYS------------------- 74
            .              :.:..|.|..|: :.:|    |..:.:.|.|
  Rat    65 VYIPKCAPGLQCQPRENEETPLRALLIGQGRCQRARGPSEETTKESKPHGGASRPRDRDRQKNPR 129

  Fly    75 ----------------GSCNACLEAVKFARRQQE----RDPGYFVPRCRKDGNFAAMQCYGNNG- 118
                            |.|...|::| ..:.|.|    ...|.:||.|...|.:...||..:.|
  Rat   130 TSAAPIRPSPVQDGEMGPCRRHLDSV-LQQLQTEVFRGGANGLYVPNCDLRGFYRKQQCRSSQGN 193

  Fly   119 ----CWCSDSQGR--PIADDNKQFRRKGKLRCRA 146
                |||.|..|:  |::.|.     :|..:|.|
  Rat   194 RRGPCWCVDPMGQPLPVSPDG-----QGSSQCSA 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	13/92 (14%)
		TY	88..139	CDD:238114	17/61 (28%)
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114
Igfbp6	NP_037236.1	IB	28..97	CDD:197525	12/68 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	92..148		5/55 (9%)
		Thyroglobulin_1	148..220	CDD:278514	21/77 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	205..226		6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000