DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and Sparcl1

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_037078.2	Gene:	Sparcl1 / 25434	RGDID:	2531	Length:	634	Species:	Rattus norvegicus

Alignment Length:	269	Identity:	65/269 - (24%)
Similarity:	92/269 - (34%)	Gaps:	88/269 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 PACAAKQGECDDNE--------GPVCGTDGQTYPTRCHLLRAQC------GGHQVSLKYSGSCNA 79
            |.|.     |.|.|        ...||||.|||.:.|||...:|      .|||:.|.|.|:|.:
  Rat   422 PHCV-----CQDPETCPPAKILDQACGTDNQTYASSCHLFATKCMLEGTKKGHQLQLDYFGACKS 481

  Fly    80 CLEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNN---GCWCSDSQGRPIADDNKQFRRKGK 141
            ......|...|       |..|.|.......||.|..|   |.:.::.|           |.|.|
  Rat   482 IPACTDFEVAQ-------FPLRMRDWLKNILMQLYEPNPKHGGYLNEKQ-----------RSKVK 528

  Fly   142 LRCRANRRDRRRLA-SHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSF 205
               :....::|.|| .|.|..                                |:|.|:.....:
  Rat   529 ---KIYLDEKRLLAGDHPIEL--------------------------------LLRDFKKNYHMY 558

  Fly   206 FRQPSLSDSHILEWQFSKLDTN-GNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANL 269
            .        :.:.|||::||.: .:::|...|:..|:..|   |....|...|.:.||..||.::
  Rat   559 V--------YPVHWQFNELDQHPADRILTHSELAPLRASL---VPMEHCITRFFEECDPNKDKHI 612

  Fly   270 NWLEWSVCF 278
            ...||..||
  Rat   613 TLKEWGHCF 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	20/52 (38%)
		TY	88..139	CDD:238114	11/53 (21%)
		SPARC_Ca_bdg	180..274	CDD:287550	19/94 (20%)
		SPARC_EC	<219..281	CDD:238155	20/61 (33%)
		TY	396..463	CDD:238114
Sparcl1	NP_037078.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	50..335
		MSCRAMM_ClfB	<95..402	CDD:411414
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	360..398
		KAZAL_FS	403..482	CDD:412159	23/64 (36%)
		EFh_SPARC_SPARCL1	485..625	CDD:320015	42/201 (21%)
		EF-hand motif	558..590	CDD:320015	8/39 (21%)
		EF-hand motif	593..623	CDD:320015	10/29 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910