DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and Sparc

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_033268.1	Gene:	Sparc / 20692	MGIID:	98373	Length:	302	Species:	Mus musculus

Alignment Length:	261	Identity:	55/261 - (21%)
Similarity:	86/261 - (32%)	Gaps:	82/261 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ACAAKQGECDDNEGPVCGTDGQTYPTRCHLLRAQC------GGHQVSLKYSGSCN---ACL--EA 83
            :|.|..||.:    .||..|.:|:.:.||....:|      .||::.|.|.|.|.   .||  |.
Mouse    99 SCPAPIGEFE----KVCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIAPCLDSEL 159

  Fly    84 VKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADDNKQFRRKGKLRCRANR 148
            .:|..|.::......|....:|                         :.|.....|.|||.:...
Mouse   160 TEFPLRMRDWLKNVLVTLYERD-------------------------EGNNLLTEKQKLRVKKIH 199

  Fly   149 RDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSD 213
            .:.:||                  |||.......::.....:|   |.:|.
Mouse   200 ENEKRL------------------EAGDHPVELLARDFEKNYN---MYIFP-------------- 229

  Fly   214 SHILEWQFSKLDTNG-NKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVC 277
               :.|||.:||.:. :..|...|:..|:..|   :....|...|.:.||:..|..:...||:.|
Mouse   230 ---VHWQFGQLDQHPIDGYLSHTELAPLRAPL---IPMEHCTTRFFETCDLDNDKYIALEEWAGC 288

  Fly   278 F 278
            |
Mouse   289 F 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	12/44 (27%)
		TY	88..139	CDD:238114	4/50 (8%)
		SPARC_Ca_bdg	180..274	CDD:287550	17/94 (18%)
		SPARC_EC	<219..281	CDD:238155	18/61 (30%)
		TY	396..463	CDD:238114
Sparc	NP_033268.1	FSL_SPARC	70..151	CDD:238649	17/55 (31%)
		EFh_SPARC_SPARC	154..293	CDD:320014	38/202 (19%)
		EF-hand motif	226..259	CDD:320014	10/52 (19%)
		EF-hand motif	261..293	CDD:320014	9/29 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910